Faculty Bibliography

Dental surgeries are among the most common outpatient procedures, yet the temporal aspects of pain resolution and the relation to longer term pain outcomes remains poorly understood. Furthermore, the risk factors for long lasting pain after common dental surgeries remain largely unknown. This prospective cohort study identified subgroups of individual pain trajectories of acute (7-day) post-operative pain after root-end resection surgery and their associated risk factors. Ninety-three patients were included in this study. Latent class mixed modeling identified seventy-nine patients (85%) in the resolving pain group, while fourteen (15%) patients were in the non-resolving pain group. Multivariate logistic regression model revealed that higher pain catastrophizing scale (PCS) score (odds ratio: 1.11, 95% CI: 1.05-1.20), chronic bodily pain (odds ratio: 7.56, 95% CI: 1.35-63.89) and pre-operative pain at the surgical site (odds ratio: 5.95, 95% CI: 1.08-42.64) associate with an increased likelihood of having non-resolving acute pain (p < 0.05). Validity of the trajectory groups was supported by the observation that the frequency of pain with neuropathic characteristics at 1 week and the frequency of ongoing pain at 1 month were higher in patients with non-resolving pain trajectories. Finally, it was found that the presence of perioperative pain and the anatomical location of the tooth were significant predictors of ongoing pain at 1 month (sub-acute pain). This study sheds light on crucial determinants of delayed pain resolution following a common dental surgery, which provides insight for future efforts at the management and prevention of prolonged post-surgical dental pain. PERSPECTIVE: Recognizing acute post-operative pain trajectories with non-resolving patterns, individual risk factors, and neuropathic qualities can identify patients needing tailored pain management strategies after routine dental surgery to prevent prolonged acute and subacute post-surgical pain.

BACKGROUND:Disparities in posttransplant outcomes persist and worsened during the COVID-19 pandemic, disproportionately affecting individuals with social risk factors. This study examined the total and residual (ie, direct) associations between individual- and neighborhood-level income and posttransplant outcomes among deceased donor kidney transplant (DDKT) and living donor kidney transplant recipients transplanted in the United States in 2020. METHODS:This retrospective cohort study linked Organ Procurement and Transplantation Network data with estimated individual annual income from LexisNexis and neighborhood median annual household income from the American Community Survey. Multivariable Cox models assessed associations between income and 3-y all-cause graft survival, patient survival, and death-censored graft survival. RESULTS:Among 14 091 DDKT recipients, lower individual income was associated with higher all-cause graft failure (adjusted hazard ratio [aHR] for lowest quartile [Q1] versus highest [Q4]: 1.37; 95% confidence interval [CI], 1.20-1.56) and death (aHR, 1.47; 95% CI, 1.26-1.72). Neighborhood income had weaker associations, though Q1 recipients still had higher all-cause graft failure (aHR, 1.17; 95% CI, 1.03-1.33) and death (aHR, 1.21; 95% CI, 1.04-1.41). In models including both income measures, only individual income remained significant. Censoring COVID-19 deaths attenuated associations for individual income, while neighborhood income was no longer significant. Among 4565 living donor kidney transplant recipients, income was not significantly associated with outcomes. CONCLUSIONS:Lower individual income predicts higher all-cause graft failure, primarily because of increased mortality in DDKT recipients. Neighborhood income has a weaker effect, particularly when censoring COVID-19 deaths. Targeted interventions are needed to improve equity in kidney transplantation, especially during public health crises.

Coaxial extrusion-based bioprinting (EBB) is an emerging technology that enables the fabrication of biomimetic tissues with precise structural and biological complexities. This three-dimensional bioprinting technique utilizes specialized concentric nozzles to facilitate the simultaneous extrusion of distinct biomaterials, enabling the fabrication of layered constructs that closely resemble native tissues. Unlike traditional extrusion-based methods, coaxial printing allows for independent control over core and shell materials. This enables multimaterial integration, and tailored microenvironments that conventional extrusion methods cannot achieve. Recent technical innovations in coaxial EBB also include improved nozzle designs and bioink formulations, which have contributed to enhanced functional mimicry of native tissues and mechanical integrity of printed constructs. Coaxial EBB has demonstrated potential in spinal cord injury repair, perfusable small-diameter vessel engineering, accurate tumor microenvironment replication for oncology research, and complex organoid systems for personalized medicine. Despite these advancements, persistent challenges in coaxial EBB include maintaining cell viability under shear stress, optimizing bioink rheology, preventing nozzle clogging, and managing regulatory considerations. Future research directions involve the development of predictive computational models and the incorporation of innovative biomaterials for dynamic functionality. Addressing these challenges would allow the full therapeutic and clinical potential of coaxial bioprinting in regenerative medicine to be achieved. This review discusses and summarizes these advancements and limitations in coaxial EBB over the last decade, with an emphasis on applications in regenerative medicine.

This article highlights the significance of 20 dental eponyms in prosthodontics, emphasizing the enduring legacy of the individuals behind them. Each name represents a pivotal advancement and a foundational contribution to the history of dentistry and prosthodontics in particular. Understanding their lives and innovations fosters a deeper appreciation of today's clinical practice, which are built on past discoveries. As current technologies become tomorrow's historical artifacts, recognizing the evolution of the field helps contextualize modern dentistry and anticipate future directions. Honoring these pioneers is essential to preserving the continuity of knowledge and valuing the individual efforts that have shaped the profession.

Do you ever wonder who is behind the names, diseases, structures, procedures, or syndromes often taught in dental or medical school? For instance, the Cusp of Carabelli on a maxillary molar, the Wharton duct of the submandibular gland, or the Eustachian tube that gives the perception of a stuffed ear before landing are three structures named after individuals who first described them centuries ago. This is a long-overdue exploration of 60 names for 53 of the most relevant eponyms, many of whom have likely been forgotten.^I.

This article, the seventh in an eight-part special issue on dental eponyms, focuses on 18 key eponyms in restorative dentistry contributed by 19 innovative dentists, scientists, and engineers. Eponyms serve as historical reminders of the legacy of individuals whose innovations have shaped clinical practice. In this paper, we explore contributions ranging from the Toffelmire matrix systems to Hollanbeck carvers and Morrison adjustable chairs. This paper underscores the importance of remembering the foundational figures in dentistry. In doing so, it reinforces the value of historical continuity and honors the lasting impact of those who advanced the field of restorative care.

This article, the second in a series of eight, highlights the lives and original works of 21 scientists whose names are preserved in 20 enduring eponyms still found in dental anatomy and histology textbooks. Though frequently referenced in education, the historical context and the original publications behind these terms are often overlooked. By revisiting their biographies and citing the original sources where each eponym was first described, this work offers a long-overdue acknowledgment of their lasting contributions to dental science.