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school:SOM

Department/Unit:Otolaryngology

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Histological detection of human papilloma virus high risk types in sinonasal inverted papillomas by in situ hybridization [Meeting Abstract]

Zafar, S; Yee, H; Wu, HH; Huan, Y; Wang, BY
ISI:000252180201641
ISSN: 0893-3952
CID: 75923

Fascin over-expression is associated with dysplastic changes in sinonasal inverted papillomas - A study of 32 cases [Meeting Abstract]

Wu, HH; Zafar, S; Chiriboga, L; Huan, Y; Wang, BY
ISI:000252181101245
ISSN: 0023-6837
CID: 75939

Aesthetic repair of small to medium-sized nasal defects

Shah, Anil R; Zoumalan, Richard; Constantinides, Minas S
Reconstruction of small and medium-sized defects of the nose poses a challenge to the facial plastic surgeon. Flaps for small to medium-sized defects most often are closed in single-staged procedures as opposed to larger-sized defects. A variety of techniques can be used including secondary intention, primary closure, full-thickness skin grafts, composite grafts, rhomboid flaps, bilobe flaps, dorsal nasal flaps, island flaps, and inferiorly based meliolabial flaps
PMID: 18286439
ISSN: 0736-6825
CID: 78690

Determination of the function of the internal branch of the superior laryngeal nerve after thyroidectomy

Wasserman, Jared M; Sundaram, Krishnamurthi; Alfonso, Antonio E; Rosenfeld, Richard M; Har-El, Gady
BACKGROUND: Several unique complications of thyroidectomy exist because of its regional anatomy; they are well studied and reported. A majority of thyroidectomy patients report vague upper aerodigestive tract complaints. Despite this, no formal assessment of the integrity of the internal branch of the superior laryngeal nerve after thyroidectomy exists in the literature. METHODS: Thirty three patients undergoing thyroidectomy were prospectively evaluated with preoperative and postoperative laryngopharyngeal sensory testing. RESULTS: Preoperatively, 16 patients (49%) reported dysphagia, and 19 (58%) complained of globus sensation. Postoperatively, 24 (73%) patients complained of dysphagia, and 25 (76%) reported globus sensation. Preoperative sensory testing showed a mean sensory threshold of 2.79 +/- 0.51 mm Hg. The mean change in thresholds postoperatively was trivial (0.07 +/- 0.29 mm Hg), and did not differ significantly from zero (p = .19). CONCLUSIONS: Although most patients report significant difficulty swallowing after thyroidectomy, the sensory nerve to the laryngopharynx remains intact and is not at risk during thyroid surgery
PMID: 17636539
ISSN: 1043-3074
CID: 142792

Feasibility of flap reconstruction in conjunction with intraoperative radiation therapy for advanced and recurrent head and neck cancer

Most, Michael D; Allori, Alexander C; Hu, Kenneth; Urken, Mark L; Persky, Mark S; Sessions, Roy B; Nussbaum, Moses; Harrison, Louis B; Frank, Douglas K; Smith, Mark L
BACKGROUND: Radiation is a known risk factor for poor wound healing. Patients undergoing intraoperative radiation therapy (IORT) typically receive higher cumulative doses to their wound beds than patients treated with conventional radiation therapy. We review our experience with IORT in patients undergoing resection of head and neck cancer and flap reconstruction. Logistics of delivery and outcomes are discussed. METHODS: A retrospective chart review was performed on all patients at Beth Israel Medical Center who underwent IORT for head and neck cancer between 2000 and 2007. Twenty-one patients receiving 22 treatments involving flap reconstruction were identified. The results of these reconstructions were evaluated for complications and functional outcome. RESULTS: All patients had complex surgical wounds of the face, upper aerodigestive tract, or neck who received IORT in conjunction with pedicled or free flap closure. Twenty-five flaps in 21 patients were performed in the setting of IORT. All patients received between 10 and 15 Gy of IORT administered directly to the wound bed. There were no perioperative mortalities. Wound breakdown occurred in three cases, all of which were treated successfully by operative revision. Functionally, most patients did well and performed similarly to historic controls for their type of reconstruction. CONCLUSIONS: Reconstruction using flaps in the context of IORT can be achieved with expectation of good wound healing in the majority of cases despite heavy cumulative doses of radiation to recipient wound beds.
PMID: 18165718
ISSN: 0023-852x
CID: 963252

Malpractice litigation after surgical injury of the spinal accessory nerve: an evidence-based analysis

Morris, Luc G T; Ziff, David J S; Delacure, Mark D
OBJECTIVE: To review the background, case characteristics, and outcomes of malpractice litigation resulting from surgical injury of the spinal accessory nerve. DESIGN: Retrospective review of indemnity insurance cases (part 1) and court trials (part 2) between January 1, 1985, and January 1, 2007. In part 1, records of the Medical Liability Mutual Insurance Company identified 41 lawsuits in New York State; part 2 was a review of a national legal database (WestLaw) that identified 81 court trials. Case details were analyzed, and awards were adjusted for inflation. RESULTS: For part 1, of 41 indemnity insurance cases, 39 (95%) involved a posterior triangle lymph node biopsy. Defendants were mainly general surgeons and otolaryngologists. Most lawsuits against surgeons (22 of 34 [65%]) were settled before trial, and only 4 of 34 (12%) were discontinued. Of these 34 cases, 28 (82%) ultimately compensated the plaintiff. The mean inflation-adjusted pretrial settlement was $264 395, and the mean settlement at trial was $443 538. Cases reaching trial received significantly higher settlements (P = .01). For part 2, 81 cases of alleged surgical injury to the spinal accessory nerve were identified. Defendant physicians were mainly general surgeons and otolaryngologists. Most operations were cervical lymph node biopsies (55 [68%]), followed by sebaceous cyst excisions (6 [7%]), neck dissections (4 [5%]), and other procedures (12 [15%]). Morbidity included weakness (81 patients [100%]), pain (30 patients [37%]), inability to work (20 patients [25%]), need for a nerve repair procedure (16 patients [20%]), deformity (9 patients [11%]), and numbness (4 patients [5%]). Types of malpractice alleged included negligent surgical technique (79 cases [98%]), lack of informed consent (17 cases [21%]), and failure to diagnose the injury (16 cases [20%]). Thirty-seven cases (46%) were decided for the defendant, 32 (40%) were decided for the plaintiff, and 12 (15%) were settled (percentages do not total 100 because of rounding). The mean inflation-adjusted settlement was $356 132, and the mean jury award was $515 968. Jury awards were significantly higher than settlements (P = .003). CONCLUSIONS: Unintended injury to the spinal accessory nerve after head and neck surgery is a significant source of malpractice litigation. Timely diagnosis and treatment of this complication are essential. Regardless of whether the medical community considers careful surgical technique and nerve preservation to be the standard of care, the legal system clearly treats it as such, awarding compensation in 82% of cases. Strategies for optimal surgical care and litigation risk reduction are discussed
PMID: 18209145
ISSN: 0886-4470
CID: 76341

Quantitative evaluation of transtemporal and facial translocation approaches to infratemporal fossa

Kuriakose, Moni A; Sorin, Alex; Sharan, Rajeev; Fishman, Andrew J; Babu, Ramesh; Delacure, Mark D
Objective: To compare the extent of exposure and surgical maneuverability provided by facial translocation and transtemporal approaches for access to the infratemporal fossa and anterolateral skull base. Materials and Methods: Surgical procedures were performed on five fresh frozen adult cadavers (ten sides) with no known pathology. Facial transfacial approaches with and without a mandibulotomy and transtemporal approaches were evaluated. Objective measures were (1) the distance from the surgical plane to designated anatomic landmarks and (2) the surgical angle of exposure. Results: Distances from the surgical plane to the anatomic reference points were comparable for most of the access procedures (3 to 6 cm). The extended midfacial translocation and bilateral facial translocation approaches did, however, provide a shorter operative distance (1 to 3 cm) for access to the infratemporal fossa and contralateral structures, respectively. The transtemporal approaches facilitate a better angle of exposure (74 to 84 degrees) to the petrotemporal region, while the transfacial approaches were superior for access to the infratemporal structures. Conclusions: Based on the results, we propose a clinical algorithm for selecting a surgical approach based on the position and extent of an infratemporal or petrotemporal lesion
PMCID:2435471
PMID: 18592023
ISSN: 1531-5010
CID: 96303

Utility of history and physical updates for ambulatory otolaryngic surgery

Lee, Scott L; Taliercio, Salvatore; Ata, Ashar; Clayton, Jessica; Parnes, Steven M
OBJECTIVES/HYPOTHESIS: Preoperative assessment is intended to identify anesthetic risk and a patient's appropriateness to undergo a proposed surgery. The timing of these assessments varies among institutions. In our ambulatory surgery center, preoperative reassessments were initially performed within 30 days of surgery (group A). Recently, this changed to require reassessments within 7 days of surgery (group B). Now, the policy mandates a preoperative reassessment within 24 hours (group C). We evaluate whether there are differences in surgical cancellations based on these new reassessment intervals. STUDY DESIGN: Retrospective operative log and chart review. METHODS: We identified 1,108 cases representative of group A. The rate of surgical cancellations for this group was compared with that of the 3,705 cases in group B and the 1,060 cases in group C. Differences were evaluated with a chi test. RESULTS: Total cancellation rates for groups A, B, and C were 3.0%, 3.3%, and 3.9%, respectively (P = .51). Cancellations secondary to a history and physical examination findings during these preoperative reassessment periods were 0.81%, 0.38%, and 0.66% for groups A, B, and C, respectively (P = .15). CONCLUSIONS: Cancellation rates for patients undergoing ambulatory otolaryngic surgery based on preoperative reassessment intervals of 30 days, 7 days, and 24 hours were similar.
PMID: 17975507
ISSN: 0023-852x
CID: 466842

Fascin over-expression is associated with dysplastic changes in sinonasal inverted papillomas - A study of 32 cases [Meeting Abstract]

Wu, HH; Zafar, S; Yee, H; Cluriboga, L; Huan, Y; Wang, BY
ISI:000252180201245
ISSN: 0893-3952
CID: 75918

Quality of life after tonsillectomy in children with recurrent tonsillitis

Goldstein, Nira A; Stewart, Michael G; Witsell, David L; Hannley, Maureen T; Weaver, Edward M; Yueh, Bevan; Smith, Timothy L; Orvidas, Laura J
OBJECTIVE: To describe changes in disease-specific and global quality of life (QOL) for children with recurrent or chronic tonsillitis at 6 months and 1 year after tonsillectomy using two validated instruments, the Tonsil and Adenoid Health Status Instrument (TAHSI) and the Child Health Questionaire-PF28 (CHQ-PF28). STUDY DESIGN AND SETTING: A multicenter, prospective observational outcomes study. RESULTS: Ninety-two children, mean age (SD) 10.6 (3.4) years, enrolled with follow-up available for 58 children at 6 months and 38 children at 1 year. The children showed significant improvements in all subscales of the TAHSI including airway and breathing, infection, health care utilization, cost of care, eating and swallowing (all P < 0.001), and behavior (P = 0.01). Significant improvements were also found on several subscales of the CHQ-PF28, such as general health perceptions, physical functioning, parental impact, and family activities (all P < 0.001). CONCLUSION/SIGNIFICANCE: This uncontrolled study provides prospective evidence of improved disease-specific and global QOL in children after tonsillectomy
PMID: 18164376
ISSN: 0194-5998
CID: 125025