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Department/Unit:Child and Adolescent Psychiatry

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Bouts of steps: The organization of infant exploration

Cole, Whitney G; Robinson, Scott R; Adolph, Karen E
Adults primarily walk to reach a new location, but why do infants walk? Do infants, like adults, walk to travel to a distant goal? We observed 30 13-month-old and 30 19-month-old infants during natural walking in a laboratory playroom. We characterized the bout structure of walking-when infants start and stop walking-to examine why infants start and stop walking. Locomotor activity was composed largely of brief spurts of walking. Half of 13-month-olds' bouts and 41% of 19-month-olds' bouts consisted of three or fewer steps-too few to carry infants to a distant goal. Most bouts ended in the middle of the floor, not at a recognizable goal. Survival analyses of the distribution of steps per bout indicated that the probability of continuing to walk was independent of the length of the ongoing bout; infants were just as likely to stop walking after five steps as after 50 steps and they showed no bias toward bouts long enough to carry them across the room to a goal. However, 13-month-olds showed an increased probability of stopping after 1-3 steps, and they did not initiate walking more frequently to compensate for their surfeit of short bouts. We propose that infants' natural walking is not intentionally directed at distant goals; rather, it is a stochastic process that serves exploratory functions. Relations between the bout structure of walking and other measures of walking suggest that locomotor exploration is constrained by walking skill in younger infants, but not in older infants.
PMCID:4801732
PMID: 26497472
ISSN: 1098-2302
CID: 2714602

A call for action regarding translational research in pediatric sleep [Letter]

Gruber, Reut; Anders, Thomas F; Beebe, Dean; Bruni, Oliviero; Buckhalt, Joseph A; Carskadon, Mary A; Cote, Kimberly; Crabtree, Valerie McLaughlin; El-Sheikh, Mona; Gozal, David; Ivanenko, Anna; Mindell, Jodi A; Owens, Judith; Redline, Susan; Shatkin, Jess P; Weiss, Shelly; Wise, Merrill S
PMID: 28923265
ISSN: 2352-7226
CID: 2708122

Fear and Missing Out: Youth Anxiety and Functional Outcomes [Review]

Swan, Anna J; Kendall, Philip C
Anxiety disorders are prevalent and associated with functional impairments. Outcome research has focused on symptom reduction, rather than positive factors such as life satisfaction and improved functioning. We review the impact of youth anxiety disorders and elevated anxiety symptoms on academic, occupational, family, social, and legal functioning. Emphasis is placed on the degree to which developmental trajectories differ for youth with and without anxiety disorders. In some areas, psychopathology generally, rather than anxiety specifically, is associated with functional impairment. Other studies support youth anxiety as a unique predictor of functional impairment. In particular, social anxiety is associated with impairments in social functioning throughout development. The short- and long-term impacts of anxiety treatment in youth are discussed. Last, research directions are suggested.
ISI:000391047600008
ISSN: 1468-2850
CID: 2697092

Significance of sniffing pattern during the acquisition of an olfactory discrimination task

Lefevre, Laura; Courtiol, Emmanuelle; Garcia, Samuel; Thevenet, Marc; Messaoudi, Belkacem; Buonviso, Nathalie
Active sampling of olfactory environment consists of sniffing in rodents. The importance of sniffing dynamics is well established at the neuronal and behavioral levels. Patterns of sniffing have been shown to be modulated by the physicochemical properties of odorants, particularly concentration and sorption. Sniffing is also heavily impacted by higher processing related to the behavioral context, emotion and attentional demand. However, how the pattern of sniffing evolves over the course of learning of an experimental olfactory conditioning is still poorly understood. We tested this question by monitoring sniffing activity, using a whole-body plethysmograph, on rats performing a two-alternative choice odor discrimination task. We followed sniff variations at different learning stages (naive, well-trained, expert). We found that during the acquisition of an odor discrimination task, rats acquired a global sniffing pattern, independent of the odor pair used. This pattern consists of a longer sampling duration, a higher sniffing frequency, and a larger amplitude. In parallel, subtle differences of sniffing between the two odors of a pair were also observed. This sniffing behavior was not only associated with a better and faster acquisition of the discrimination task but was also transferred to other odor sets and refined after a long-term pause so as to reduce the sampling duration and maintain a specific sniffing frequency. Our results provide additional arguments that sniffing is a complex sensorimotor act that is strongly affected by olfactory learning.
PMID: 27343936
ISSN: 1872-7549
CID: 2698852

BANKING THE FUTURE: ADOLESCENT CAPACITY TO CONSENT TO BIOBANK RESEARCH [Meeting Abstract]

McGregor, Kyle A; Lahren, Alexa; Ott, Mary A
ISI:000373428800035
ISSN: 1879-1972
CID: 2690102

Willingness to Disclose Sexually Transmitted Infection Status to Sex Partners Among College-Aged Men in the United States

Pfeiffer, Elizabeth J; McGregor, Kyle A; Van Der Pol, Barbara; Hardy Hansen, Cathlene; Ott, Mary A
Disclosure of sexually transmitted infections (STIs) to sexual partners is critical to the prevention, treatment, and control of STIs. We examine personal intra and interpersonal influences on willingness to disclose STI status among college-aged men. Participants (n = 1064) were aged 17 to 24 years and recruited from a variety of university and community venues. Using independent-samples t test, Pearson chi test, and binary logistic regression, we examined the relationship between willingness to disclose an STI and intrapersonal and interpersonal factors, including age, masculinity values, interpersonal violence, partner cell phone monitoring, alcohol and/or drug use, condom use, number and characteristics of sex partners, and previous STI. Results reveal that among college-aged men, type of sex partner and masculinity values are significant variables in predicting whether or not an individual is willing to disclose. These data can inform STI control programs to more effectively address the complex issues associated with STI disclosure to sex partners.
PMCID:4748392
PMID: 26859810
ISSN: 1537-4521
CID: 2690062

Methods and Procedures for Measuring Comorbid Disorders: Medical

Chapter by: Cervantes, Paige; Jang, Jina
in: COMORBID CONDITIONS AMONG CHILDREN WITH AUTISM SPECTRUM DISORDERS by Matson, JL [Eds]
NEW YORK : SPRINGER, 2016
pp. 65-90
ISBN:
CID: 2690362

Autism spectrum disorders: management over the lifespan

Matson, Johnny L; Cervantes, Paige E; Peters, W Jason
INTRODUCTION: For the majority of the autism spectrum disorder (ASD) population, symptoms begin within the first years of life and associated difficulties continue throughout the lifespan. Currently, the research literature focuses more heavily on problems in childhood. However, given that adulthood accounts for the majority of life, more focus should be placed on evidence-based, lifelong treatment and management strategies for ASD. Areas covered: This paper reviews the topic of lifelong ASD management, primarily emphasizing issues in adolescence and adulthood. Among the topics discussed are timing and methods of treatment across the lifespan, and specific intervention targets that emerge or are more relevant to this older cohort. Expert commentary: Several advances have been made in the treatment of adolescent and adult specific issues. However, research should continue to focus on these areas. Greater focus on coordination of care across disciplines and policy regarding ASD management over the lifespan is also required.
PMID: 27322023
ISSN: 1744-8360
CID: 2690132

Hearing Impairment, Autism Spectrum Disorder, and Developmental Functioning in Infants and Toddlers

Burns, Claire O; Matson, Johnny L; Cervantes, Paige E; Jiang, Xinrui; Estabillo, Jasper A
Autism spectrum disorder (ASD) tends to co-occur with other psychiatric disorders and medical conditions, and identification of comorbidities is crucial for appropriate intervention. Currently, little research has examined the relationship between ASD and deafness or hearing impairment (D/HI). The present study aimed to examine the effects of ASD and D/HI on autism symptomology as measured by the Baby and Infant Screen for Children with aUtIsm Traits (BISCUIT), and developmental functioning in infants and toddlers as measured by the Battelle Developmental Inventory, Second Edition (BDI-2). Specific developmental domains were also investigated. This study compared children with atypical development (n = 24), comorbid atypical development and D/HI (n = 24), ASD only (n = 24), and comorbid ASD and D/HI (n = 24). The results indicated that an ASD diagnosis was a stronger indicator of ASD symptomology, overall developmental functioning, adaptive skills, personal-social skills, and communication skills than D/HI. However, the interaction between ASD and D/HI was more dynamic for the motor and cognitive domains. The results of the current study emphasize the importance of improved assessment techniques to identify both ASD and D/HI when they co-occur. Future research should be conducted to further elucidate the interaction of ASD and D/HI, as well as investigate these comorbidities in older samples.
ISI:000379021300001
ISSN: 1573-3580
CID: 2690372

Attention-deficit hyperactivity disorder and autism spectrum disorder

Chapter by: Cortese, S
in: Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder by
pp. 79-91
ISBN: 9783319296951
CID: 2687082