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Department/Unit:Child and Adolescent Psychiatry

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11202


Altered Self-perceptions in Adolescents with Major Depressive Disorder [Meeting Abstract]

Gabbay, Vilma; Case, Julia; Johnson, Amy; Hanna, Amira; Milham, Michael
ISI:000345905002033
ISSN: 0893-133x
CID: 4903772

Analyze This! [Editorial]

Henderson, Schuyler W
ISI:000336560400017
ISSN: 1527-5418
CID: 1877442

Not Painless [Editorial]

Henderson, Schuyler W
ISI:000333770200014
ISSN: 1527-5418
CID: 1877422

Shifts in shame [Editorial]

Henderson, Schuyler W
This editorial presents an overview of the two books discussed in the issue Journal of the American Academy of Child & Adolescent Psychiatry. The first book is about fighting stigma that argues against several myths. It is important to keep debates around stigma alive and to investigate the myths and realities of stigma, rather than just assuming that stigma is an all-powerful force, that we are necessarily bound to our patients with a shared stigma, or that it explains more than it really does. The second book examines treatment for a behavior that has been imbued with all the hallmarks of stigma, including shame and secrecy.
PSYCH:2013-44560-017
ISSN: 1527-5418
CID: 1901592

Spectrums

Henderson, Schuyler W
This article provides an overview of the books featured in the present issue of Journal of the American Academy of Child & Adolescent Psychiatry book forum section. The books encounter some of the challenges that come with moving a unique identity into a diagnostic construct. Feng Liu reviews a book about evaluating and assessing autism spectrum disorders (ASD), which is how we as professional caregivers move individuals into a group. Janella Hong takes us in a different direction, looking at a book that explores identity from within a group whose members often found meaning by being part of that group; this particular book quickly became significantly dated, not because the experiences it describes belong to a different era, but because formally, in certain circles, that group vanished and became part of another group. Finally, Aaron Roberto reviews a novel about an adolescent with ASD who works "in the real world, " imaginative literature with a poignant message about how a child with an ASD might find it difficult to become the next Tommy Hilfiger. Three books, 3 genres, all of which explore the relationship of the individual to the group.
PSYCH:2014-03709-017
ISSN: 1527-5418
CID: 1901582

Repetitions

Henderson, Schuyler W
This editorial briefs the articles featured in section "Book Forum" of this issue of Journal of the American Academy of Child & Adolescent Psychiatry. One of the books is about trichotillomania, skin picking, and other body focused repetitive disorders with a wonderfully vivid image of professional life as a type of constant repetitious act, always in (comic) motion. The other one is about medications: specifically, a book about adverse effects. The list of potential adverse effects grows with every new case report, letter to the editor, or revelation that a drug that was not supposed to cause a particular side effect actually does.
PSYCH:2014-07514-016
ISSN: 1527-5418
CID: 1901572

Development, calibration and performance of an HIV transmission model incorporating natural history and behavioral patterns: application in South Africa

McCormick, Alethea W; Abuelezam, Nadia N; Rhode, Erin R; Hou, Taige; Walensky, Rochelle P; Pei, Pamela P; Becker, Jessica E; DiLorenzo, Madeline A; Losina, Elena; Freedberg, Kenneth A; Lipsitch, Marc; Seage, George R
Understanding HIV transmission dynamics is critical to estimating the potential population-wide impact of HIV prevention and treatment interventions. We developed an individual-based simulation model of the heterosexual HIV epidemic in South Africa and linked it to the previously published Cost-Effectiveness of Preventing AIDS Complications (CEPAC) International Model, which simulates the natural history and treatment of HIV. In this new model, the CEPAC Dynamic Model (CDM), the probability of HIV transmission per sexual encounter between short-term, long-term and commercial sex worker partners depends upon the HIV RNA and disease stage of the infected partner, condom use, and the circumcision status of the uninfected male partner. We included behavioral, demographic and biological values in the CDM and calibrated to HIV prevalence in South Africa pre-antiretroviral therapy. Using a multi-step fitting procedure based on Bayesian melding methodology, we performed 264,225 simulations of the HIV epidemic in South Africa and identified 3,750 parameter sets that created an epidemic and had behavioral characteristics representative of a South African population pre-ART. Of these parameter sets, 564 contributed 90% of the likelihood weight to the fit, and closely reproduced the UNAIDS HIV prevalence curve in South Africa from 1990-2002. The calibration was sensitive to changes in the rate of formation of short-duration partnerships and to the partnership acquisition rate among high-risk individuals, both of which impacted concurrency. Runs that closely fit to historical HIV prevalence reflect diverse ranges for individual parameter values and predict a wide range of possible steady-state prevalence in the absence of interventions, illustrating the value of the calibration procedure and utility of the model for evaluating interventions. This model, which includes detailed behavioral patterns and HIV natural history, closely fits HIV prevalence estimates.
PMCID:4035281
PMID: 24867402
ISSN: 1932-6203
CID: 5297472

Planning an Action: A Developmental Progression in Tool Use

Keen, Rachel; Lee, Mei-Hua; Adolph, Karen
How children pick up a tool reveals their ability to plan an action with the end goal in mind. When presented with a spoon whose handle points away from their dominant hand, children between infancy and 8 years of age progress from using an awkward ulnar grip that causes food to spill from the spoon to consistently using a radial grip. At 4 years of age children's grip strategies are highly variable, including the awkward grips of infancy and use of the non-dominant hand, but they also employ adult-like grips never seen in infancy. By 8 years of age the infantile ulnar grip has completely disappeared and is replaced by more mature and effective grips that indicates better planning for the end goal.
PMCID:4061986
PMID: 24954996
ISSN: 1040-7413
CID: 1651582

Spared piriform cortical single-unit odor processing and odor discrimination in the tg2576 mouse model of Alzheimer's disease

Xu, Wenjin; Lopez-Guzman, Mirielle; Schoen, Chelsea; Fitzgerald, Shane; Lauer, Stephanie L; Nixon, Ralph A; Levy, Efrat; Wilson, Donald A
Alzheimer's disease is a neurodegenerative disorder that is the most common cause of dementia in the elderly today. One of the earliest reported signs of Alzheimer's disease is olfactory dysfunction, which may manifest in a variety of ways. The present study sought to address this issue by investigating odor coding in the anterior piriform cortex, the primary cortical region involved in higher order olfactory function, and how it relates to performance on olfactory behavioral tasks. An olfactory habituation task was performed on cohorts of transgenic and age-matched wild-type mice at 3, 6 and 12 months of age. These animals were then anesthetized and acute, single-unit electrophysiology was performed in the anterior piriform cortex. In addition, in a separate group of animals, a longitudinal odor discrimination task was conducted from 3-12 months of age. Results showed that while odor habituation was impaired at all ages, Tg2576 performed comparably to age-matched wild-type mice on the olfactory discrimination task. The behavioral data mirrored intact anterior piriform cortex single-unit odor responses and receptive fields in Tg2576, which were comparable to wild-type at all age groups. The present results suggest that odor processing in the olfactory cortex and basic odor discrimination is especially robust in the face of amyloid beta precursor protein (AbetaPP) over-expression and advancing amyloid beta (Abeta) pathology. Odor identification deficits known to emerge early in Alzheimer's disease progression, therefore, may reflect impairments in linking the odor percept to associated labels in cortical regions upstream of the primary olfactory pathway, rather than in the basic odor processing itself.
PMCID:4152226
PMID: 25181487
ISSN: 1932-6203
CID: 1173742

Training and Education in Clinical Psychology in the Context of the Patient Protection and Affordable Care Act [Review]

Chor, Ka Ho Brian; Olin, Su-chin Serene; Hoagwood, Kimberly Eaton
The Patient Protection and Affordable Care Act of 2010 (ACA) is revamping the access, quality, and financing of the health and mental health systems. However, its impact on training and education in clinical psychology is unclear. This article aims to identify specific components of the ACA, in particular the Mental and Behavioral Health Education and Training Grants, that are expected to affect training and education in the field. The article further connects the ACA with four paradigm shifts in clinical psychology that have broad implications for training and educationevidence-based practices, research methodology, interprofessionalism, and the quality indicator movement. The overarching goal of this article is to begin timely discussions on the future directions of the field under the current healthcare reform.
ISI:000337629800001
ISSN: 1468-2850
CID: 2341882