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school:SOM

Department/Unit:Otolaryngology

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7749


The prognostic value of round window electrical stimulation in cochlear implant patients

Waltzman, S B; Cohen, N L; Shapiro, W H; Hoffman, R A
The use of preoperative round window stimulation has been advocated for its possible predictive value in cochlear implant patients. We have attempted to correlate cause of deafness, preoperative radiologic study, and postoperative stimulability and performance with preoperative stimulation. Round window stimulation procedures consisted of measurements of electrical thresholds and comfort levels, gap detection, and temporal difference limen. Radiologic studies were performed using high-resolution computerized semi-axial and coronal tomography with 1.5-millimeter overlapping cuts. Patient performance was measured using a standard audiologic test battery. Sixteen postlingually, profoundly deaf adults who received the Nucleus multichannel cochlear implant were studied. All 16 patients who responded to preoperative stimulation had acceptable CT scans for the ear operated on and stimulated postoperatively with the prosthesis. The lowest level at which a patient could reliably detect a gap between two signals ranged from 10 to 150 milliseconds, which was not predictive. For the temporal difference limen task, the patients who could reliably identify the longer of two pulses when the difference was less than 100 milliseconds did achieve varying amounts of open-set speech discrimination postoperatively. In summary, results indicate that the preoperative psychoacoustic electrical stimulation test battery provides useful information in predicting postoperative performance
PMID: 2117716
ISSN: 0194-5998
CID: 141150

Parotid disease associated with human immunodeficiency virus infection

Sperling, N M; Lin, P T
Cystic parotid enlargement is a newly recognized manifestation of HIV infection. It commonly occurs early in the spectrum of HIV-related illnesses and may be part of LAS. Serologic confirmation of HIV infection and CT imaging usually establishes the diagnosis. Cytologic or histopathologic evaluation may be required for diagnostic confirmation and for management.
PMID: 2401224
ISSN: 0145-5613
CID: 1066842

Controlled laryngoplasty for vocal cord medialization: a technique using tissue expansion

Kuriloff DB; Goldsher M; Blaugrund SM; Krespi YP
Laryngeal framework surgery has become an increasingly popular alternative to Teflon injection for vocal rehabilitation. Vocal cord medialization requires custom tailoring of the implant's size and shape to optimize individual vocal quality, whether it be via the interposition of Silastic implants between the thyroid ala and the inner thyroid perichondrium or through a cartilage window. A new technique is described for vocal cord medialization using an implanted miniature tissue expander. Intraoperative and postoperative vocal cord medialization was achieved in a canine model by controlled percutaneous filling of a remote injection valve. The implants were well tolerated and allowed continued control of vocal cord position for several weeks. Using this technique, vocal quality can be fine-tuned with a degree of precision not previously possible. The advantages, limitations, and technical aspects of expansion laryngoplasty are discussed
PMID: 2348741
ISSN: 0023-852x
CID: 26351

Cystic parotid masses in HIV infection

Sperling, N M; Lin, P T; Lucente, F E
Cystic enlargement of the parotid gland is a newly described manifestation of infection with human immunodeficiency virus (HIV). A review of 15 such patients with respect to clinical presentation, natural history, and management is presented. Follow-up ranges from 1 to 27 months, averaging 10 months. In 47% of the patients, parotid swelling was the chief complaint leading to the diagnosis of HIV infection. T-cell analysis revealed the tendency for this lesion to occur in the early stages of immunodeficiency when T-cell counts are high. Histologic examination revealed findings resembling benign lymphoepithelial lesion. It is felt that these lesions are a local manifestation of a systemic disease and treatment should be tailored with this in mind. Surgical excision may not be necessary. Fine-needle aspiration (FNA) was found to be useful diagnostically and therapeutically. Recognition of this entity is essential for the head and neck specialist in providing an early diagnosis of HIV infection.
PMID: 2361865
ISSN: 1043-3074
CID: 1066852

Language growth in children with expressive language delay [Letter]

Ruben, R J
PMID: 2339043
ISSN: 0031-4005
CID: 1270062

Pediatric human immunodeficiency virus infection: an otolaryngologist's perspective

Sculerati N; Borkowsky W
Children with human immunodeficiency virus (HIV) frequently have recurrent otitis media, chronic rhinorrhea, parotitis, cough and other common pediatric otolaryngologic problems. As these complaints often occur before more unusual opportunistic infections or pulmonary conditions prompt a diagnosis of acquired immunodeficiency syndrome (AIDS), members of our specialty are liable to see HIV-positive children before infection with the virus has been recognized. Children with HIV infection are also likely to be referred to us after diagnosis, as is any immunosuppressed child with otolaryngologic infections. These children may require procedures such as bronchoscopy, sinus irrigations or tympanocentesis. The subject of this review is the natural history of pediatric HIV infection with special emphasis on otolaryngologic manifestations and recommendations for safe techniques of examination and treatment
PMID: 2192074
ISSN: 0381-6605
CID: 14564

Recurrent pleomorphic adenomas of the parotid gland

Myssiorek, D; Ruah, C B; Hybels, R L
Twenty-seven patients with recurrent pleomorphic adenomas of the parotid gland were seen. This study confirms that superficial parotidectomy with identification and dissection of the facial nerve greatly decreases the incidence of recurrent benign pleomorphic adenoma, and, in the small number that recur, are easier to cure. All lumps in the parotid area should be approached in the same manner, with the surgeon prepared to isolate the facial nerve and perform superficial parotidectomy. This technique is successful because it avoids dissection near the tumor capsule, which is the major cause of recurrence. The procedure recommended for treatment of patients to remove the first recurrent tumor is total parotidectomy and excision of the previous scar. This vigorous approach is dictated by the increasing difficulty of removing further recurrent tumors. Only 67% of patients with recurrent tumors ultimately achieve a tumor-free status. Experienced surgeons can preserve the facial nerve even after multiple operations
PMID: 2361864
ISSN: 1043-3074
CID: 73762

OTITIS-MEDIA AND HEARING-LOSS IN TURNER SYNDROME

Sculerati, N; Ledesmamedina, J; Finegold, DN; Stool, SE
ISI:A1990DH40400011
ISSN: 0886-4470
CID: 31866

Use of principal components analysis to develop a composite score as a primary outcome variable in a clinical trial. The VA Cooperative Study Group on Cochlear Implantation

Henderson, W G; Fisher, S G; Cohen, N; Waltzman, S; Weber, L
This article describes the use of principal components analysis to derive a composite score from a battery of 24 audiologic tests. The composite score is being used as the primary outcome variable in a clinical trial comparing the efficacy of three cochlear implant devices for people with bilateral, profound hearing loss. The first principal component from the within-class pooled variance-covariance matrix over four time periods was chosen to establish the coefficients for the composite score. This component accounted for 61% of the total variance of the 24 audiologic tests. The first principal component had its largest coefficients associated with the most difficult audiologic tests. The mean composite score of all patients improved over time; some patients showed dramatic improvement. The changes in the composite score over time were also closely related to subjective impressions of implant performance by the patient, audiologist, and otolaryngologist
PMID: 2163815
ISSN: 0197-2456
CID: 141151

OTOLARYNGOLOGIC MANAGEMENT OF POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE IN CHILDREN

Sculerati, N; Arriaga, M
ISI:A1990DJ07200006
ISSN: 0003-4894
CID: 31865