Faculty Bibliography

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school:SOM

Department/Unit:Neuroscience Institute

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13349

Single and rare cell analysis-amplification methods. T7 based amplification protocols

Chapter by: Ginsberg, Stephen D
in: Microarrays in inflammation by Bosio, Andreas; Gerstmayer, Bernhard [Eds]
Basel : Birkhäuser, c2008
pp. 81-94
ISBN: 9783764383343
CID: 448572

Gene expression abnormalities mark the progression of Alzheimer's disease

Chapter by: Ginsberg, SD; Che, S; Counts, SE; Mufson, EJ
in: Research progress in Alzheimer and dementia : [Vol. 3] by Sun, Maio-Kun [Eds]
Hauppauge, N.Y. : Nova Biomedical ; Lancaster : Gazelle [distributor], 2008
pp. 25-58
ISBN: 1600219608
CID: 448582

Nonresective surgical management of refractory epilepsy : callosotomy and vagal stimulation

Chapter by: Madsen, Joseph R; Louie, Kenway
in: Principles and practice of pediatric neurosurgery by Albright, A; Adelson, P; Pollack, Ian F (Eds)
New York : Thieme, 2008
pp. 1096-1114
ISBN: 9783131146922
CID: 3702942
Neuro-degenerative diseases. 2008:5(3-4):228-31.DOI: 10.1159/000113710

Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease

Counts, Scott E; He, Bin; Che, Shaoli; Ginsberg, Stephen D; Mufson, Elliott J
BACKGROUND: Fibers containing galanin (GAL) enlarge and hyperinnervate cholinergic basal forebrain (CBF) nucleus basalis (NB) neurons in late-stage Alzheimer's disease (AD), yet the physiological consequences of this phenomenon are unclear. OBJECTIVE: To determine whether GAL hyperinnervation of cholinergic NB neurons modulates the expression of genes critical to cholinergic transmission [e.g. acetylcholine (ACh) metabolism and ACh receptors] in AD. METHODS: Single-cell gene expression profiling was used to compare cholinergic mRNA levels in non-GAL-hyperinnervated NB neurons in tissue autopsied from cases classified as having no cognitive impairment (NCI) or late-stage AD (AD/GAL-) and in GAL-hyperinnervated (AD/GAL+) NB neurons from the same AD subjects. RESULTS: AD/GAL+ cells displayed a significant upregulation in choline acetyltransferase (ChAT) mRNA expression compared to NCI and AD/GAL- cells. CONCLUSION: GAL fiber hyperinnervation of cholinergic NB neurons upregulates the expression of ChAT, the synthetic enzyme for ACh, suggesting that GAL regulates the cholinergic tone of CBF neurons in AD
PMCID:2826456
PMID: 18322398
ISSN: 1660-2862
CID: 135335
Society for Neuroscience abstract viewer & itinerary planner. 2008:38.DOI:

Gender differences in the expression of NGF receptors in single cholinergic nucleus basalis neurons during the progression of Alzheimer's disease [Meeting Abstract]

Counts, S. E.; Che, S.; Ginsberg, S. D.; Mufson, E. J.
BIOSIS:PREV201200172882
ISSN: 1558-3635
CID: 459162
Society for Neuroscience abstract viewer & itinerary planner. 2008:38.DOI:

MicroRNA (miRNA) expression profiling using the miRNA signature sequence amplification (SSAM) technology in human postmortem brain tissues and in animal models of neurodegeneration [Meeting Abstract]

Che, S.; Ginsberg, S. D.
BIOSIS:PREV201200148907
ISSN: 1558-3635
CID: 459232

Diffusible hydrogen peroxide generated by synaptic activity inhibits axonal dopamine release in striatum

Chapter by: Avshalumov, Marat V; Patel, Jyoti C; Bao, Li; MacGregor, Duncan G; Sidlo, Zsuzsanna; Rice, Margaret E
in: Beyond the synapse: Cell-cell signaling in synaptic plasticity by Fields, R. Douglas. [Eds]
New York, NY, US: Cambridge University Press, 2008
pp. 181-192
ISBN: 978-0-521-86914-0
CID: 5015

Umwelt : a psychomotor functional event

Chapter by: Llinas R
in: Neurobiology of "Umwelt" : how living beings perceive the world by
Berlin : Springer, 2008
pp. 29-37
ISBN: 3540858962
CID: 5252
Society for Neuroscience abstract viewer & itinerary planner. 2008:38.DOI:

Rab GTPase gene up regulation within individual cholinergic nucleus basalis neurons correlates with cognitive decline in Alzheimer's disease and mild cognitive impairment [Meeting Abstract]

Ginsberg, S. D.; Che, S.; Counts, S. E.; Wuu, J.; Nixon, R. A.; Mufson, E. J.
BIOSIS:PREV201200148909
ISSN: 1558-3635
CID: 458922

Single cell gene expression analysis in human postmortem brain tissues and animal models of neurodegeneration

Chapter by: Ginsberg, Stephen D
in: Biomacromolecular mass spectrometry research progress by Koenig, Simone [Eds]
New York : Nova Science Publishers, c2008
pp. 109-110
ISBN: 1604564873
CID: 453022