Faculty Bibliography

This paper will provide information on a recent Breakthrough Series Collaborative (BSC) conducted by the National Child Traumatic Stress Network on Using Trauma-Informed Child Welfare Practice to Improve Foster Care Placement Stability. Information on this particular BSC will be provided, followed by initial findings gathered from an evaluation of the BSC and metrics gathered by each of the nine participating teams throughout the BSC process. Specific trauma-informed promising strategies adopted by teams are presented along with recommendations for next steps.

Fregoli syndrome (FS) is commonly associated with verbal threats and aggressive behavior. We present a case of Fregoli syndrome leading to an assault. We discuss the possible underdiagnosis of FS, associated risk for aggression, and strategies to reduce that risk.

Differences between child welfare- and non-child welfare-involved families regarding barriers to child mental health care, attendance, program satisfaction, and relationship with facilitators are examined for a multiple family group service delivery model aimed at reducing childhood disruptive behaviors. Although child welfare-involved caregivers reported more treatment barriers and less program satisfaction than non-child-welfare-involved families, no significant differences exist between groups on average total sessions attended and attendance rates over time.

The use of structural magnetic resonance imaging (sMRI) and diffusion tensor imaging (DTI) in animal models of neuropathology is of increasing interest to the neuroscience community. In this work, we present our approach to create optimal translational studies that include both animal and human neuroimaging data within the frameworks of a study of post-natal neuro-development in intra-uterine cocaine-exposure. We propose the use of non-invasive neuroimaging to study developmental brain structural and white matter pathway abnormalities via sMRI and DTI, as advanced MR imaging technology is readily available and automated image analysis methodology have recently been transferred from the human to animal imaging setting. For this purpose, we developed a synergistic, parallel approach to imaging and image analysis for the human and the rodent branch of our study. We propose an equivalent design in both the selection of the developmental assessment stage and the neuroimaging setup. This approach brings significant advantages to study neurobiological features of early brain development that are common to animals and humans but also preserve analysis capabilities only possible in animal research. This paper presents the main framework and individual methods for the proposed cross-species study design, as well as preliminary DTI cross-species comparative results in the intra-uterine cocaine-exposure study.

In this paper, we propose a novel approach for intensity based atlas construction from a population of anatomical images, that estimates not only a template representative image but also a common optimal parameterization of the anatomical variations evident in the population. First, we introduce a discrete parameterization of large diffeomorphic deformations based on a finite set of control points, so that deformations are characterized by a low dimensional geometric descriptor. Second, we optimally estimate the position of the control points in the template image domain. As a consequence, control points move to where they are needed most to capture the geometric variability evident in the population. Third, the optimal number of control points is estimated by using a log - L1 sparsity penalty. The estimation of the template image, the template-to-subject mappings and their optimal parameterization is done via a single gradient descent optimization, and at the same computational cost as independent template-to-subject registrations. We present results that show that the anatomical variability of the population can be encoded efficiently with these compact and adapted geometric descriptors.

The purpose of this study was to evaluate the importance of adult attachment and relationship beliefs (dysfunctional expectations and implicit theories of relationships) for predicting interdependence in emerging adults' romantic relationships. College students at Fairleigh Dickinson University's Teaneck and Madison campuses were recruited from undergraduate psychology courses. Those students who consented to participate completed a battery of self-report measures. Bivariate correlations were computed among all variables of interest. None of the predictor variables were associated with overall ratings of relationship interdependence. Several multiple regression models were then conducted in order to assess whether attachment anxiety predicted interdependence, and whether the different relationship beliefs moderated this association. All models predicting relationship interdependence were non-significant, however some of the models predicting Strength of Influence, a subscale of interdependence, were significant. Older age and greater endorsement of the Mindreading is Expected and Disagreement is Dangerous beliefs were predictive of greater Strength of Influence scores. Exploratory analyses indicated that the interaction between gender and dysfunctional relationship beliefs approached significance in the model predicting Strength of Influence. The destiny and growth beliefs (i.e. implicit theories of relationships) were largely unrelated to either attachment anxiety or the outcome of interest, and no moderation effect was found for either belief. This study adds to our understanding of the phenomenology of relationship beliefs in emerging adulthood, particularly how such beliefs influence close relationships. In comparison to married adults, for whom dysfunctional beliefs are detrimental to relationship functioning, emerging adults who endorsed dysfunctional beliefs in this study simultaneously reported positive relationship functioning, as indicated by greater influence of their romantic partners. Such findings suggest that dysfunctional beliefs may be developmentally appropriate in emerging adulthood and may only become harmful to relationships later in the lifespan.

Posttraumatic stress disorder (PTSD) is a common and disabling anxiety disorder that may occur in the aftermath of exposure to potentially traumatic life events. PTSD is moderately heritable, but few specific molecular variants accounting for this heritability have been identified. Genes regulating the hypothalamic-pituitary-adrenal (HPA) axis, such as corticotrophin-releasing hormone type 1 receptor gene (CRHR1), have been implicated in traumatic-stress related phenotypes but have yet to be studied in relation to PTSD. The present study sought to examine the relation between 9 single nucleotide polymorphisms (SNPs) in the CRHR1 gene and posttraumatic stress symptoms in a prospective study of pediatric injury patients (n=103) who were first assessed in the acute aftermath of their injury at the hospital. Results indicated that multiple SNPs were associated with acute symptoms at a univariate level, and after correction for multiple testing, rs12944712 was significantly related to acute PTSD symptoms. Longitudinal latent growth curve analyses suggest that rs12944712 is also related to both acute symptom level and trajectory of symptoms over time. The present study adds support for the role of CRHR1 in the stress response following potentially traumatic event exposure in youth. It should be noted that the sample size in this study was small, and therefore statistical power was low; following, results from this study should be considered preliminary. Although results are not definitive, the findings from this study warrant future replication studies on how variation in this gene relates to response to traumatic event exposure in youth

The goal of this paper is to synthesize available data to help guide policy and programmatic initiatives for families with substance abuse problems who are involved with the child welfare system, and identify gaps in the research base preventing further refinement of practices in this area. To date, Family Treatment Drug Court and newly developed home-based substance abuse treatment interventions appear the most effective at improving substance abuse treatment initiation and completion in child welfare populations. Research is needed to compare the efficacy of these two approaches, and examine cost and child well-being indicators in addition to substance abuse treatment and child welfare outcomes