Try a new search

Format these results:

Searched for:

school:SOM

Department/Unit:Population Health

Total Results:

12955


Duration of general anaesthetic exposure in early childhood and long-term language and cognitive ability

Ing, C; Hegarty, M K; Perkins, J W; Whitehouse, A J O; DiMaggio, C J; Sun, M; Andrews, H; Li, G; Sun, L S; von Ungern-Sternberg, B S
Background: The anaesthetic dose causing neurotoxicity in animals has been evaluated, but the relationship between duration of volatile anaesthetic (VA) exposure and neurodevelopment in children remains unclear. Methods: Data were obtained from the Western Australian Pregnancy Cohort (Raine) Study, with language (Clinical Evaluation of Language Fundamentals: Receptive [CELF-R] and Expressive [CELF-E] and Total [CELF-T]) and cognition (Coloured Progressive Matrices [CPM]) assessed at age 10 yr. Medical records were reviewed, and children divided into quartiles based on total VA exposure duration before age three yr. The association between test score and exposure duration quartile was evaluated using linear regression, adjusting for patient characteristics and comorbidity. Results: Of 1622 children with available test scores, 148 had documented VA exposure and were split into the following quartiles: 25 to 35 to 60 min. Compared with unexposed children, CELF-T scores for children in the first and second quartiles did not differ, but those in the third and fourth quartiles had significantly lower scores ([3 rd quartile - Unexposed] -5.3; 95% confidence interval [CI], (-10.2 - -0.4), [4 th quartile - Unexposed] -6.2; 95% CI, (-11.6 - -0.9). CELF-E showed similar findings, but significant differences were not found in CELF-R or CPM for any quartile. Conclusions: Children with VA exposures 35 min had lower total and expressive language scores. It remains unclear if this is a dose-response relationship, or if children requiring longer exposures for longer surgeries have other clinical reasons for lower scores.
PMCID:5901742
PMID: 28969309
ISSN: 1471-6771
CID: 2723632

Variation in Prescription Drug Coverage for Triptans: Analysis of Insurance Formularies [Meeting Abstract]

Minen, Mia T; Lindberg, Kate; Langford, Aisha; Loder, Elizabeth
ISI:000410068300117
ISSN: 1468-2982
CID: 2713562

The Current Limits of Calorie Labeling and the Potential for Population Health Impact

Breck, Andrew; Mijanovich, Tod; Weitzman, Beth C; Elbel, Brian
By mid-2018, federal policy will require chain restaurants with more than 20 U.S. locations to include calorie information on their menus. Despite high expectations that this policy would encourage healthier eating, most studies of local policies to mandate calorie labels have demonstrated little impact on consumer choice. In this article, the authors adapt Burton and Kees's (2012) conceptual framework for eating behavior change to better understand the limited impact of these policies thus far. Using two surveys of fast-food consumers in Philadelphia, the authors estimate the percentage who might reasonably be expected to respond to calorie labels given the requirements of the Burton and Kees model. They find that as few as 8% of fast-food consumers meet all the model's requirements and, therefore, would be expected to change their eating behavior as a result of calorie information. The authors use the model and findings to consider how calorie-labeling policy could be improved for greater impact.
ISI:000415386200004
ISSN: 1547-7207
CID: 2793672

Utilization of behavioral treatment in migraine patients who visit a Headache Center: A Cross-Sectional Study [Meeting Abstract]

Minen, Mia; Boubour, Alexandra; Halpern, Audrey; Berk, Thomas; Seng, Elizabeth
ISI:000410068300068
ISSN: 1468-2982
CID: 2713572

Perceptions of Safety Among LGBTQ People Following the 2016 Pulse Nightclub Shooting

Stults, Christopher B; Kupprat, Sandra A; Krause, Kristen D; Kapadia, Farzana; Halkitis, Perry N
The goals of this manuscript are two-fold. First, we provide a brief reaction to this journal's "Special Section: Reflections on the Orlando Massacre on its First Anniversary." Second, we present findings from a study on perceptions of safety among LGBTQ individuals following the Pulse shooting. These issues are discussed within the historical context of hate crimes experienced by the LGBTQ population (Herek), media coverage following the shooting (Hancock & Halderman), and the immediate reaction of LGBTQ graduate students to the event (Jackson). Our study sought to examine differences in perceptions of personal and peer safety by race/ethnicity, gender identity, and sexual orientation among a large, diverse sample of LGBTQ people. Findings from our study indicate that there were differences in perceptions of personal safety by gender identity, and differences in perceptions of peer safety by gender identity and sexual orientation. These findings also suggest that subgroups of the LGBTQ community with more marginalized gender and sexual identities (e.g., female, transgender, genderqueer, bisexual, queer respondents) perceived more concerns related to safety, on average, than subgroups with relatively more privilege (e.g., gay, male). Elevated safety concern may exacerbate multiple minority stress burden, a known driver of poor health outcomes among LGBTQ people. These findings are a call to action to healthcare providers to be well informed and trained to provide the appropriate care and counseling referrals that can address the safety-related concerns of LGBTQ individuals in the aftermath of identity-related attacks.
PMCID:5693229
PMID: 29159198
ISSN: 2329-0382
CID: 2791622

Text message reminders for improving patient appointment adherence in an office-based buprenorphine program: A feasibility study

Tofighi, Babak; Grazioli, Frank; Bereket, Sewit; Grossman, Ellie; Aphinyanaphongs, Yindalon; Lee, Joshua David
BACKGROUND AND OBJECTIVES: Missed visits are common in office-based buprenorphine treatment (OBOT). The feasibility of text message (TM) appointment reminders among OBOT patients is unknown. METHODS: This 6-month prospective cohort study provided TM reminders to OBOT program patients (N = 93). A feasibility survey was completed following delivery of TM reminders and at 6 months. RESULTS: Respondents reported that the reminders should be provided to all OBOT patients (100%) and helped them to adhere to their scheduled appointment (97%). At 6 months, there were no reports of intrusion to their privacy or disruption of daily activities due to the TM reminders. Most participants reported that the TM reminders were helpful in adhering to scheduled appointments (95%), that the reminders should be offered to all clinic patients (95%), and favored receiving only TM reminders rather than telephone reminders (95%). Barriers to adhering to scheduled appointment times included transportation difficulties (34%), not being able to take time off from school or work (31%), long clinic wait-times (9%), being hospitalized or sick (8%), feeling sad or depressed (6%), and child care (6%). CONCLUSIONS: This study demonstrated the acceptability and feasibility of TM appointment reminders in OBOT. Older age and longer duration in buprenorphine treatment did not diminish interest in receiving the TM intervention. Although OBOT patients expressed concern regarding the privacy of TM content sent from their providers, privacy issues were uncommon among this cohort. Scientific Significance Findings from this study highlighted patient barriers to adherence to scheduled appointments. These barriers included transportation difficulties (34%), not being able to take time off from school or work (31%), long clinic lines (9%), and other factors that may confound the effect of future TM appointment reminder interventions. Further research is also required to assess 1) the level of system changes required to integrate TM appointment reminder tools with already existing electronic medical records and appointment records software; 2) acceptability among clinicians and administrators; and 3) financial and resource constraints to healthcare systems. (Am J Addict 2017;XX:1-6).
PMID: 28799677
ISSN: 1521-0391
CID: 2664212

Validation of the TAPS-1: A Four-Item Screening Tool to Identify Unhealthy Substance Use in Primary Care

Gryczynski, Jan; McNeely, Jennifer; Wu, Li-Tzy; Subramaniam, Geetha A; Svikis, Dace S; Cathers, Lauretta A; Sharma, Gaurav; King, Jacqueline; Jelstrom, Eve; Nordeck, Courtney D; Sharma, Anjalee; Mitchell, Shannon G; O'Grady, Kevin E; Schwartz, Robert P
BACKGROUND: The Tobacco, Alcohol, Prescription Medication, and Other Substance use (TAPS) tool is a combined two-part screening and brief assessment developed for adult primary care patients. The tool's first-stage screening component (TAPS-1) consists of four items asking about past 12-month use for four substance categories, with response options of never, less than monthly, monthly, weekly, and daily or almost daily. OBJECTIVE: To validate the TAPS-1 in primary care patients. DESIGN: Participants completed the TAPS tool in self- and interviewer-administered formats, in random order. In this secondary analysis, the TAPS-1 was evaluated against DSM-5 substance use disorder (SUD) criteria to determine optimal cut-points for identifying unhealthy substance use at three severity levels (problem use, mild SUD, and moderate-to-severe SUD). PARTICIPANTS: Two thousand adult patients at five primary care sites. MAIN MEASURES: DSM-5 SUD criteria were determined via the modified Composite International Diagnostic Interview. Oral fluid was used as a biomarker of recent drug use. KEY RESULTS: Optimal frequency-of-use cut-points on the self-administered TAPS-1 for identifying SUDs were >/= monthly use for tobacco and alcohol (sensitivity = 0.92 and 0.71, specificity = 0.80 and 0.85, AUC = 0.86 and 0.78, respectively) and any reported use for illicit drugs and prescription medication misuse (sensitivity = 0.93 and 0.89, specificity = 0.85 and 0.91, AUC = 0.89 and 0.90, respectively). The performance of the interviewer-administered format was similar. When administered first, the self-administered format yielded higher disclosure rates for past 12-month alcohol use, illicit drug use, and prescription medication misuse. Frequency of use alone did not provide sufficient information to discriminate between gradations of substance use problem severity. Among those who denied drug use on the TAPS-1, less than 4% had a drug-positive biomarker. CONCLUSIONS: The TAPS-1 can identify unhealthy substance use in primary care patients with a high level of accuracy, and may have utility in primary care for rapid triage.
PMCID:5570743
PMID: 28550609
ISSN: 1525-1497
CID: 2575052

Group Education Sessions for Women Veterans Who Experienced Sexual Violence: Qualitative Findings

Dognin, Joanna; Sedlander, Erica; Jay, Melanie; Ades, Veronica
INTRODUCTION: The impact of sexual violence (SV) on mental health, self-care, and interpersonal relationships is profound and poses special challenges to health care delivery. Reproductive health care merits special attention because the care required may be linked to reminders of past abuse. We explored facilitators and barriers affecting the use of reproductive health services among women veterans with a history of SV. METHOD: Between June and September 2015, we conducted 2 focus groups and 3 general education sessions with 27 female veterans with a history of SV at 1 medical center. We analyzed transcripts according to applied thematic analysis and used Nvivo software for data management and retrieval. RESULTS: Three main themes emerged from the focus groups and education sessions. PARTICIPANTS: (a) expressed a desire for greater agency in relation to the control they have over their bodies and medical care; (b) described how posttraumatic stress symptoms are retriggered during medical care; and (c) expressed needs for additional education, peer and provider support within the medical system. DISCUSSION: For women with a history of SV, multiple individual and systemic barriers complicate how they utilize reproductive health services. Group education sessions were an effective mode of support, information and connection to other women within the Veterans Health Administration. (PsycINFO Database Record
PMID: 28414479
ISSN: 1939-0602
CID: 2705352

Early Childhood Home Visiting [Historical Article]

Duffee, James H; Mendelsohn, Alan L; Kuo, Alice A; Legano, Lori A; Earls, Marian F
High-quality home-visiting services for infants and young children can improve family relationships, advance school readiness, reduce child maltreatment, improve maternal-infant health outcomes, and increase family economic self-sufficiency. The American Academy of Pediatrics supports unwavering federal funding of state home-visiting initiatives, the expansion of evidence-based programs, and a robust, coordinated national evaluation designed to confirm best practices and cost-efficiency. Community home visiting is most effective as a component of a comprehensive early childhood system that actively includes and enhances a family-centered medical home.
PMID: 28847981
ISSN: 1098-4275
CID: 3070452

Quantifying the Impact of Type 2 Diabetes on Brain Perfusion Using Deep Neural Networks

Chapter by: Saghafi, Behrouz; Garg, Prabhat; Wagner, Benjamin C; Smith, S Carrie; Xu, Jianzhao; Madhuranthakam, Ananth J; Jung, Youngkyoo; Divers, Jasmin; Freedman, Barry I; Maldjian, Joseph A; Montillo, Albert
in: Deep learning in medical image analysis and multimodal learning for clinical decision support : Third International Workshop, DLMIA 2017, and 7th International Workshop, ML-CDS 2017, held in conjunction with MICCAI 2017 Quebec City, QC,... by
pp. 151-159
ISBN: 9783319675572
CID: 4319022