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Telemedicine and the evaluation of cognitive impairment: the additive value of neuropsychological assessment

Harrell, Kathryn M; Wilkins, Stacy S; Connor, Megan K; Chodosh, Joshua
INTRODUCTION: The number of people in the United States living with dementia is projected to rise to over 7.1 million in the next 12 years, representing a 40% increase from current levels. This anticipated "dementia tsunami" has led to a recent state and national policy emphasis on early detection, improved care quality, reduced caregiver burden, and increased access to care. The ability to achieve these objectives is limited by few dementia specialists in rural and small communities and the challenges of travel to and within congested urban regions for dementia patients and their caregivers. Telemedicine is one such means for responding to this lack of access to subspecialty assessment and care. We describe our early experiences with this technology applied to neuropsychological assessments, with data from 31 patients. METHODS: As part of an interdisciplinary dementia care demonstration project, clinical video teleconferencing provides real-time high resolution video interactions between dementia subspecialists in a major metropolitan medical center and patients in 3 outlying clinics located 180, 150, and 100 miles away. Comprehensive neuropsychological assessments, designed to address referral questions related to neurocognitive disorders via clinical video teleconferencing, are conducted as one component of interdisciplinary care. OUTCOMES: Eighty-seven percent of patients referred for neuropsychological assessment had an inaccurate neurocognitive diagnosis at the time of referral. Unmet and unrecognized mental health treatment needs were identified in over 77% of patients. In addition, acceptance was good for patients, caregivers, and clinicians. DISCUSSION: Teleneuropsychology is proving to be an excellent resource for clarifying cognitive and psychiatric diagnoses, and integrating individual strengths, weaknesses, and preferences into treatment and care plans used by other health care providers, patients, and caregivers.
PMID: 24913209
ISSN: 1525-8610
CID: 1498632

Baby carrots: Chew on this [Newspaper Article]

Caplan, Arthur L; Elbel, Brian; Bragg, Marie A
In 2012, fast-food companies spent $4.6 billion on ads, while $116 million was spent advertising fruits and vegetables. Because young people see tons of food ads on adult-targeted programs, it makes sense to cite the whole $4.6 billion figure
PROQUEST:1560020213
ISSN: 1085-6706
CID: 1490132

Neurodevelopmental outcomes after initial childhood anesthetic exposure between ages 3 and 10 years

Ing, Caleb H; DiMaggio, Charles J; Whitehouse, Andrew J O; Hegarty, Mary K; Sun, Ming; von Ungern-Sternberg, Britta S; Davidson, Andrew J; Wall, Melanie M; Li, Guohua; Sun, Lena S
INTRODUCTION: Epidemiologic studies examining the association between anesthetic exposure and neurodevelopmental outcomes have primarily focused on exposures occurring under 3 years of age. In this study, we assess outcomes associated with initial anesthetic exposure occurring between 3 and 10 years of age. METHODS: We used data from the Western Australian Pregnancy Cohort (Raine) Study to examine the risk of cognitive deficit at age 10 in children with initial anesthetic exposure between 3 and 5 years and between 5 and 10 years of age compared with children unexposed at those ages. The cohort included 2868 children born from 1989 to 1992 evaluated using a range of neuropsychological tests. A modified multivariable Poisson regression model was used to determine the adjusted association of initial anesthetic exposure in each age group with outcomes. RESULTS: Exposed and unexposed children were found to have similar neuropsychological test results except for the McCarron Assessment of Neuromuscular Development (MAND) motor function scores. Even after adjusting for demographic and comorbidity differences, children exposed to anesthesia had a higher risk of motor deficit after initial exposure between ages 3 and 5 years (adjusted risk ratio, 2.32; 95% confidence interval, 1.42-3.79) and between 5 and 10 years (adjusted risk ratio, 2.33; 95% confidence interval, 1.21-4.48) compared with unexposed children. CONCLUSIONS: Initial exposure to anesthesia after age 3 had no measurable effects on language or cognitive function. Decreased motor function was found in children initially exposed after age 3 even after accounting for comorbid illness and injury history. These results suggest that there may be distinct windows of vulnerability for different neurodevelopmental domains in children.
PMID: 25144506
ISSN: 0898-4921
CID: 1481952

Comparative analysis of outcome measures used in examining neurodevelopmental effects of early childhood anesthesia exposure

Ing, Caleb H; DiMaggio, Charles J; Malacova, Eva; Whitehouse, Andrew J; Hegarty, Mary K; Feng, Tianshu; Brady, Joanne E; von Ungern-Sternberg, Britta S; Davidson, Andrew J; Wall, Melanie M; Wood, Alastair J J; Li, Guohua; Sun, Lena S
INTRODUCTION: Immature animals exposed to anesthesia display apoptotic neurodegeneration and neurobehavioral deficits. The safety of anesthetic agents in children has been evaluated using a variety of neurodevelopmental outcome measures with varied results. METHODS: The authors used data from the Western Australian Pregnancy Cohort (Raine) Study to examine the association between exposure to anesthesia in children younger than 3 yr of age and three types of outcomes at age of 10 yr: neuropsychological testing, International Classification of Diseases, 9th Revision, Clinical Modification-coded clinical disorders, and academic achievement. The authors' primary analysis was restricted to children with data for all outcomes and covariates from the total cohort of 2,868 children born from 1989 to 1992. The authors used a modified multivariable Poisson regression model to determine the adjusted association of anesthesia exposure with outcomes. RESULTS: Of 781 children studied, 112 had anesthesia exposure. The incidence of deficit ranged from 5.1 to 7.8% in neuropsychological tests, 14.6 to 29.5% in International Classification of Diseases, 9th Revision, Clinical Modification-coded outcomes, and 4.2 to 11.8% in academic achievement tests. Compared with unexposed peers, exposed children had an increased risk of deficit in neuropsychological language assessments (Clinical Evaluation of Language Fundamentals Total Score: adjusted risk ratio, 2.47; 95% CI, 1.41 to 4.33, Clinical Evaluation of Language Fundamentals Receptive Language Score: adjusted risk ratio, 2.23; 95% CI, 1.19 to 4.18, and Clinical Evaluation of Language Fundamentals Expressive Language Score: adjusted risk ratio, 2.00; 95% CI, 1.08 to 3.68) and International Classification of Diseases, 9th Revision, Clinical Modification-coded language and cognitive disorders (adjusted risk ratio, 1.57; 95% CI, 1.18 to 2.10), but not academic achievement scores. CONCLUSIONS: When assessing cognition in children with early exposure to anesthesia, the results may depend on the outcome measure used. Neuropsychological and International Classification of Diseases, 9th Revision, Clinical Modification-coded clinical outcomes showed an increased risk of deficit in exposed children compared with that in unexposed children, whereas academic achievement scores did not. This may explain some of the variation in the literature and underscores the importance of the outcome measures when interpreting studies of cognitive function.
PMID: 24694922
ISSN: 0003-3022
CID: 1481962

Reasons for emergency department use: do frequent users differ?

Doran, Kelly M; Colucci, Ashley C; Wall, Stephen P; Williams, Nick D; Hessler, Robert A; Goldfrank, Lewis R; Raven, Maria C
Objectives To examine patients' reasons for using the emergency department (ED) for low-acuity health complaints, and determine whether reasons differed for frequent ED users versus nonfrequent ED users. Study Design Prospective cross-sectional survey. Methods Patients presenting to an urban public hospital for low-acuity health complaints were surveyed about their reasons for visiting the ED rather than a private doctor's office or clinic. Patients with 3 or more visits to the study hospital ED over the past year were classified as frequent ED users. Multivariable logistic regression was used to determine if frequent ED users gave different reasons for ED use than nonfrequent ED users, while controlling for differences in other baseline patient characteristics. Results 940 patients, including 163 frequent ED users, completed the study questionnaire. Commonly cited reasons for using the ED were that coming to the ED was easier than making a clinic appointment (82.3% agreed); the problem could not wait (78.8%); they didn't know how to make a clinic appointment (66.7%); they felt the ED provided better care (56.7%); and they believed the clinic would cost more (54.8%). After controlling for other patient characteristics, there were no significant differences found in reasons for ED use given by frequent versus nonfrequent ED users. Conclusions Frequent ED users gave similar reasons for using the ED for low-acuity health complaints compared with nonfrequent ED users. Access, convenience, cost, and quality concerns, as well as feeling that ED care was needed, were all commonly cited as reasons for using the ED.
PMID: 25730349
ISSN: 1088-0224
CID: 1480362

FACILITATED FAMILY CAREGIVER ASSESSMENT OF DEMENTIA SYMPTOMS [Meeting Abstract]

Galvin, J
ISI:000346337501419
ISSN: 1758-5341
CID: 1477292

Clinical efficacy and safety of peginterferon beta-1a in patients with relapsing-remitting multiple sclerosis: 2-year data from the pivotal phase 3 ADVANCE study [Meeting Abstract]

Kieseier, BC; Balcer, L; Boyko, A; Pelletier, J; Arnold, DL; Liu, S; Zhu, Y; Seddighzadeh, A; Sheikh, S; Hung, S; Deykin, A
ISI:000347674000197
ISSN: 1432-1459
CID: 1471292

Brief action planning to facilitate behavior change and support patient self-management [Note]

Gutnick, Damara; Reims, Kathy; Davis, Connie; Gainforth, Heather; Jay, Melanie; Cole, Steven
Objective: To describe Brief Action Planning (BAP), a structured, stepped-care self-management support technique for chronic illness care and disease prevention. Methods: A review of the theory and research supporting BAP and the questions and skills that comprise the technique with provision of a clinical example. Results: BAP facilitates goal setting and action planning to build self-efficacy for behavior change. It is grounded in the principles and practice of Motivational Interviewing and evidence-based constructs from the behavior change literature. Comprised of a series of 3 questions and 5 skills, BAP can be implemented by medical teams to help meet the self-management support objectives of the Patient-Centered Medical Home. Conclusion: BAP is a useful self-management support technique for busy medical practices to promote health behavior change and build patient self-efficacy for improved long-term clinical outcomes in chronic illness care and disease prevention
EMBASE:2014483234
ISSN: 1079-6533
CID: 1463462

Good midlife dietary habits may increase likelihood of healthy aging [Note]

Perez, Hector; Jay, Melanie
EMBASE:2014492464
ISSN: 1079-6533
CID: 1463452

Are non-nutritive sweetened beverages comparable to water in weight loss trials? [Note]

Creighton, S; Jay, M
EMBASE:2014930220
ISSN: 1079-6533
CID: 1463422