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Establishing Consensus on the Treatment of Toxicodendron Dermatitis

Butt, Melissa; Marks, James G; Flamm, Alexandra
BACKGROUND:Toxicodendron dermatitis (TD) is a common form of allergic contact dermatitis that affects millions of Americans every year. Studies have shown that although there are general recommendations for the treatment of TD, there are no treatment algorithms for clinicians to follow when patients present with TD. OBJECTIVE:The objective of this study was to achieve consensus on the treatment of TD to create practical guidelines for physicians who treat TD. METHODS:Data were collected from March 2020 to April 2021. This study included semistructured focus groups and a Delphi Study with dermatologists to achieve consensus. RESULTS:A total of 51 dermatologists were included in the Delphi. Final agreement with proposed severity criteria ranged from 90.9% to 100.0%. Primary indicators of disease severity were body surface area, presence and severity of pruritus, and anatomic locations of eruptions with 77.4% agreement. Final agreement for the treatment algorithm was over the threshold majority agreement at 67.6%. CONCLUSIONS:Literature guiding the treatment of TD is scarce. The use of the Delphi method and focus groups can help expand dermatological resources both within dermatology and to other specialties that may need to treat skin conditions.
PMID: 35481848
ISSN: 2162-5220
CID: 5399292

Associations of Internalized Skin Bias With Age, Adverse Psychopathology, and Health-Related Quality of Life Among Patients With Hidradenitis Suppurativa: A Cross-sectional Analysis

Butt, Melissa; Rigby, Andrea; Leslie, Douglas L; Foulke, Galen T; Flamm, Alexandra; Kirby, Joslyn S; Chinchilli, Vernon M
IMPORTANCE:Hidradenitis suppurativa (HS) is a chronic autoinflammatory disease that is highly associated with affective disorders such as depression and anxiety. Recent studies have shown that patients with HS may also endorse high levels of internalized skin bias (ISB). This redirection of skin disease-related social stigma toward oneself may also play an important role in the associations between adverse psychopathology (eg, depression, anxiety) and health-related quality of life (HRQOL). OBJECTIVES:To evaluate the associations of ISB with other core outcomes in HS and to determine if ISB may mediate the associations between adverse psychopathological outcomes and impaired HRQOL. DESIGN, SETTING, AND PARTICIPANTS:A cross-sectional study of adult patients with HS recruited from 1 academic medical center as well as through virtual social and recruitment networks. Eligible participants completed an online survey comprised of 4 survey instruments along with demographic and disease history information from April 1, 2021, to July 15, 2021. MAIN OUTCOMES AND MEASURES:Measures included the Internalized Skin Bias Questionnaire (ISBQ), Burns Anxiety Inventory, the Beck Depression Inventory-II, the Hidradenitis Suppurativa Quality of Life (HiSQOL) instrument, along with demographic and disease history information. The primary outcome was HRQOL as measured by the HiSQOL. Data were analyzed in July through August 2021. RESULTS:The survey was completed by 230 of 279 patients (82.4%; mean [SD] age, 39.2 [11.2] years; 209 [90.9%] identified as female, 203 [88.7%] as not Hispanic, 178 [77.7%] as White). Depression and anxiety were shown to be a substantial burden in this sample, with 56.5% of participants' scores qualifying for moderate or greater anxiety and 45.7% moderate or greater depression. The mean (SD) HRQOL scores were moderately high at 34.5 (16.7), indicating strong levels of impairment. There was a moderate correlation between ISBQ score and depression (r = 0.67); and fair correlations with HRQOL (r = 0.52) and anxiety (r = 0.56). Therefore, ISB appears to positively mediate the associations between depression and anxiety (estimated proportions of total effect that were mediated, 38.7% and 24.9%, respectively) and HRQOL. After controlling for age, disease severity, and disease duration, both ISB and anxiety were positive predictors of impaired HRQOL. CONCLUSIONS AND RELEVANCE:This cross-sectional study found that ISB was associated with adverse psychopathology and impaired HRQOL in patients with HS. Furthermore, ISB appears to mediate the associations of depression and anxiety with HRQOL. Future studies are needed to design interventions targeted at addressing adverse psychopathology associated with ISB and improving HRQOL and well-being for patients with HS.
PMCID:8928088
PMID: 35293961
ISSN: 2168-6084
CID: 5399282

Characterizing demographics and cost of care for dyshidrotic eczema

Gladys, Taylor E; Maczuga, Steven; Flamm, Alexandra
BACKGROUND:Dyshidrotic eczema (DE) is a common form of eczema affecting the hands, feet, or both areas. To date, there has been little research examining demographics and cost burden associated with this disease. OBJECTIVE:This study seeks to characterize the demographics of patients affected and the direct costs of care associated with DE. METHODS:This is a retrospective analysis utilizing insurance claim information from IBM MarketScan. Pertinent data including demographic information, healthcare provider type, medications prescribed, and average cost of care were identified using the ICD 10 code L30.1 for DE for the year 2018. RESULTS:In 2018, 34 932 patients filed claims for DE, with 61% female and an average age of 37 years at first diagnosis. DE was mostly seen in employees from the service industry and the manufacturing of durable goods. The total annual direct cost was US $11 738 985. Average annual costs, however, did vary based on type of treating healthcare provider, level of care, and medications prescribed. CONCLUSIONS:Patients with DE can face an economic burden due to their disease and providers should aim to recognize this disease and its treatments to minimize healthcare costs for patients and improve quality of life.
PMID: 34773262
ISSN: 1600-0536
CID: 5399252

The Final Rule for 2022: What's New and How Changes in the Medicare Physician Fee Schedule and Quality Payment Program Affect Dermatologists

Flamm, Alexandra
The Centers for Medicare & Medicaid Services (CMS) 2022 final rule, which went into effect on January 1, 2022, contains updates affecting the practice of dermatology. This article reviews many of the changes to the Medicare Physician Fee Schedule (PFS) and Quality Payment Program (QPP) and their impact on clinical practice.
PMID: 35659803
ISSN: 2326-6929
CID: 5399302

Herpes zoster in an immunocompetent young patient following mRNA-1273 vaccine for COVID-19: A case report

Nawaz, Najiba; Samaan, Christen; Flamm, Alexandra
ORIGINAL:0016420
ISSN: 2574-1624
CID: 5412512

Clinical data registries as a vital tool for academic dermatology [Meeting Abstract]

Mittal, A.; Marks, J.; Butt, M.; Simmers, J.; Flamm, A.
ISI:000829693000509
ISSN: 0022-202x
CID: 5412472

Chopra, Shara; Sinharoy, Ankita; Flamm, Alexandra
ORIGINAL:0016419
ISSN: 2574-1624
CID: 5412502

Reducing Discomfort and Irritation Related to Surgical Loop Masks in the Era of COVID-19: A Quality Improvement Initiative

Sakya, Surav M; Svoboda, Ryan M; Kim, Yesul; Flamm, Alexandra
PMCID:8607921
PMID: 33654021
ISSN: 2162-5220
CID: 5399212

Advocacy Update: Is Your Practice Equipped to Handle Looming Changes in Dermatopathology?

Bridges, Alina G; Flamm, Alexandra; Siegel, Daniel M
In July 2021, the Centers for Medicare & Medicaid Services (CMS) published a proposed fee schedule that will negatively impact practices that perform dermatopathology services. In this article, we review the proposed new and improved codes and values for pathology consultation codes as well as new payment rates. We also discuss the proposed 2022 quality payment program (QPP), and we provide an update on the 21st Century Cures Act (Cures Act) and its impact on dermatopathology reports.
PMID: 35100533
ISSN: 2326-6929
CID: 5399272

Commentary on Characterization of Biopsies by Dermatologists and Nonphysician Providers in the Medicare Population: A Rapidly Changing Landscape [Comment]

Flamm, Alexandra; Siegel, Daniel M
PMID: 34366405
ISSN: 1524-4725
CID: 5399232