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Requesting an Autopsy of the Dead Donor Rule: Improving, Not Abandoning, the Guiding Rule in Organ Donation [Comment]

Schiff, Tamar; Caplan, Arthur
PMID: 38829594
ISSN: 1536-0075
CID: 5665012

Adequate information about clinical trial results must be given to participants

Dal-Ré, Rafael; Caplan, Arthur L; Holm, Søren; Sofat, Reecha; Stephens, Richard
PMID: 38719999
ISSN: 1546-170x
CID: 5658432

Bioethics' Duty to Conference in Qatar: Reply to Magnus [Editorial]

Jecker, Nancy S; Savulescu, Julian; Caplan, Arthur; Capron, Alexander; McMillan, John; Ghaly, Mohammed; Ortiz Millán, Gustavo; Atuire, Caesar; McMahan, Jeff; Chuan, Voo Teck; Bélisle-Pipon, Jean-Christophe; Viswani, Vina; Ravitsky, Vardit
PMID: 38529964
ISSN: 1536-0075
CID: 5644672

Standing on the Shoulders of Giant Artificial Intelligence Bots: Artificial Intelligence Can and Therefore Must Now Elevate Equity in Health Professional Education

Chickering, Miriam J.; Frank, Erica; Caplan, Arthur L.
ISSN: 2773-0654
CID: 5620742

Research involving the recently deceased: ethics questions that must be answered

Parent, Brendan; Kates, Olivia S; Arap, Wadih; Caplan, Arthur; Childs, Brian; Dickert, Neal W; Homan, Mary; Kinlaw, Kathy; Lang, Ayannah; Latham, Stephen; Levan, Macey L; Truog, Robert D; Webb, Adam; Root Wolpe, Paul; Pentz, Rebecca D
Research involving recently deceased humans that are physiologically maintained following declaration of death by neurologic criteria-or 'research involving the recently deceased'-can fill a translational research gap while reducing harm to animals and living human subjects. It also creates new challenges for honouring the donor's legacy, respecting the rights of donor loved ones, resource allocation and public health. As this research model gains traction, new empirical ethics questions must be answered to preserve public trust in all forms of tissue donation and in the practice of medicine while respecting the legacy of the deceased and the rights of donor loved ones. This article suggests several topics for immediate investigation to understand the attitudes and experiences of researchers, clinical collaborators, donor loved ones and the public to ensure research involving the recently deceased advances ethically.
PMID: 38071588
ISSN: 1473-4257
CID: 5589392

Consideration and Disclosure of Group Risks in Genomics and Other Data-Centric Research: Does the Common Rule Need Revision?

Chapman, Carolyn Riley; Quinn, Gwendolyn P; Natri, Heini M; Berrios, Courtney; Dwyer, Patrick; Owens, Kellie; Heraty, Síofra; Caplan, Arthur L
Harms and risks to groups and third-parties can be significant in the context of research, particularly in data-centric studies involving genomic, artificial intelligence, and/or machine learning technologies. This article explores whether and how United States federal regulations should be adapted to better align with current ethical thinking and protect group interests. Three aspects of the Common Rule deserve attention and reconsideration with respect to group interests: institutional review board (IRB) assessment of the risks/benefits of research; disclosure requirements in the informed consent process; and criteria for waivers of informed consent. In accordance with respect for persons and communities, investigators and IRBs should systematically consider potential group harm when designing and reviewing protocols, respectively. Research participants should be informed about any potential group harm in the consent process. We call for additional public discussion, empirical research, and normative analysis on these issues to determine the right regulatory and policy path forward.
PMID: 38010648
ISSN: 1536-0075
CID: 5617612

The legacy of Covid denialThe Deadly Rise of Anti-science: A Scientist's Warning Peter J. Hotez Johns Hopkins University Press, 2023. 240 pp

Caplan, Arthur
A physician warns of the broader implications of pandemic backlash.
PMID: 37676938
ISSN: 1095-9203
CID: 5598972

The American Association for Thoracic Surgery 2023 Expert Consensus Document: Adult cardiac transplantation utilizing donors after circulatory death

Schroder, Jacob N; Scheuer, Sarah; Catarino, Pedro; Caplan, Arthur; Silvestry, Scott C; Jeevanandam, Valluvan; Large, Stephen; Shah, Ashish; MacDonald, Peter; Slaughter, Mark S; Naka, Yoshifumi; Milano, Carmelo A
PMID: 37318399
ISSN: 1097-685x
CID: 5595112

Why the Gene Was (Mis)Placed at the Center of American Health Policy [Book Review]

Owens, Kellie; Caplan, Arthur L
Abstract In Tyranny of the Gene: Personalized Medicine and Its Threat to Public Health (Knopf, 2023), James Tabery traces the ascendance of personalized or precision medicine in America, arguing that America's emphasis on genetics offers more hype than transformational power. In his examination of the power struggles, social relationships, and technological advances that centered the gene in American health policy, Tabery demonstrates how an intensive focus on genetics draws attention away from both the fundamental causes of health disparities and more-effective changes that could be made to developmental, physical, and social environments. American policy-makers, health care institutions, funders, and bioethicists should not let the technological shine and attractive politics of personalized medicine continue to replace the hard but necessary work of addressing sociopolitical causes of disease and illness.
ISSN: 0093-0334
CID: 5568812

Protect newborn screening programs [Letter]

Owens, Kellie; Chapman, Carolyn; Caplan, Arthur
PMID: 36996201
ISSN: 1095-9203
CID: 5463382