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The legacy of Covid denialThe Deadly Rise of Anti-science: A Scientist's Warning Peter J. Hotez Johns Hopkins University Press, 2023. 240 pp

Caplan, Arthur
A physician warns of the broader implications of pandemic backlash.
PMID: 37676938
ISSN: 1095-9203
CID: 5563872

The American Association for Thoracic Surgery 2023 Expert Consensus Document: Adult cardiac transplantation utilizing donors after circulatory death

Schroder, Jacob N; Scheuer, Sarah; Catarino, Pedro; Caplan, Arthur; Silvestry, Scott C; Jeevanandam, Valluvan; Large, Stephen; Shah, Ashish; MacDonald, Peter; Slaughter, Mark S; Naka, Yoshifumi; Milano, Carmelo A
PMID: 37318399
ISSN: 1097-685x
CID: 5560692

Why the Gene Was (Mis)Placed at the Center of American Health Policy [Book Review]

Owens, Kellie; Caplan, Arthur L
Abstract In Tyranny of the Gene: Personalized Medicine and Its Threat to Public Health (Knopf, 2023), James Tabery traces the ascendance of personalized or precision medicine in America, arguing that America's emphasis on genetics offers more hype than transformational power. In his examination of the power struggles, social relationships, and technological advances that centered the gene in American health policy, Tabery demonstrates how an intensive focus on genetics draws attention away from both the fundamental causes of health disparities and more-effective changes that could be made to developmental, physical, and social environments. American policy-makers, health care institutions, funders, and bioethicists should not let the technological shine and attractive politics of personalized medicine continue to replace the hard but necessary work of addressing sociopolitical causes of disease and illness.
ISSN: 0093-0334
CID: 5568812

Protect newborn screening programs [Letter]

Owens, Kellie; Chapman, Carolyn; Caplan, Arthur
PMID: 36996201
ISSN: 1095-9203
CID: 5463382

Confronting the evolution and expansion of anti-vaccine activism in the USA in the COVID-19 era

Carpiano, Richard M; Callaghan, Timothy; DiResta, Renee; Brewer, Noel T; Clinton, Chelsea; Galvani, Alison P; Lakshmanan, Rekha; Parmet, Wendy E; Omer, Saad B; Buttenheim, Alison M; Benjamin, Regina M; Caplan, Arthur; Elharake, Jad A; Flowers, Lisa C; Maldonado, Yvonne A; Mello, Michelle M; Opel, Douglas J; Salmon, Daniel A; Schwartz, Jason L; Sharfstein, Joshua M; Hotez, Peter J
PMID: 36871571
ISSN: 1474-547x
CID: 5432512

Perspectives surrounding fertility preservation and posthumous reproduction for adolescent and young adults with terminal cancer: Survey of allied health professionals

Barrett, Francesca; Sutter, Megan E; Campo-Engelstein, Lisa; Sampson, Amani; Caplan, Arthur; Lawrence, Morgan; Vadaparampil, Susan T; Quinn, Gwendolyn P
BACKGROUND:While all reproductive-aged individuals with cancer should be offered fertility preservation (FP) counseling, there is little guidance over offers to adolescent and young adults (AYA) with terminal diagnoses, especially when considering posthumous assisted reproduction (PAR). The Enriching Communication skills for Health professionals in Oncofertility (ECHO/ENRICH) trains Allied Health Professionals (AHPs) to improve communication with AYAs with cancer. Little is known about AHPs' role in assisting in FP and PAR decisions. METHODS:This is a cross-sectional survey of ECHO/ENRICH trainees' attitudes and experience with FP and PAR in AYA with terminal cancer. RESULTS:The response rate was 61% (365/601). While 69% felt comfortable discussing FP with terminal AYA after ECHO/ENRICH training, 85% desired further education. The majority (88%) agreed FP should be an option for AYA with cancer, though some agreed offering FP provided false hope (16%) or was a waste of resources (7%). Most shared that avoidance of FP discussions was common practice, especially in the medically fragile, late-stage disease, or among minors. Many attributed lack of conversations to oncology team goals. Only 9% had prior experience with PAR. Many were conflicted about how PAR reproductive material should be gifted and who should be permitted to use PAR. Several raised moral concerns for PAR, or discomfort advising family. Many voiced desire for additional PAR-specific education. CONCLUSION/CONCLUSIONS:ECHO/ENRICH trainees had varied levels of exposure to FP in terminal AYA and limited experiences with PAR. Many expressed uncertainties with PAR, which may be alleviated with further training and transparent institutional policies.
PMID: 36226382
ISSN: 2045-7634
CID: 5361032

'Time out'-more transparency is required in 'Just-in-time' consent [Letter]

Dal-Ré, Rafael; Caplan, Arthur L; Voo, Teck Chuan
PMID: 36460540
ISSN: 1879-0828
CID: 5374222

Informed consent process in the I-SPY COVID trial is questionable [Letter]

Dal-Ré, Rafael; Caplan, Arthur L; Voo, Teck Chuan
PMID: 36283909
ISSN: 1879-0828
CID: 5359382

United in Big Data? Exploring scholars' opinions on academic-industry partnership and the use of corporate data in digital behavioral research

Favaretto, Maddalena; De Clercq, Eva; Caplan, Arthur; Elger, Bernice Simone
The growing amount of data produced through digital technologies holds great promise for advancing behavioral research. Scholars worldwide now have the chance to access an incredible amount of personal information, thanks to the digital trace users continuously leave behind them. Private corporations play a crucial role in this scenario as the leading collectors of data on users, thus creating new incentives for partnerships between academic institutions and private companies. Due to the concerns that academic-company partnerships might raise and the ethical issues connected with Big Data research, our study explores the challenges and opportunities associated with the academic use of corporate data. We conducted 39 semi-structured interviews with academic scholars (professors, senior researchers, and postdocs) involved in Big Data research in Switzerland and the United States. We also investigated their opinions on using corporate data for scholarly research. Researchers generally showed an interest in using corporate data; however, they coincidentally shared ethical reservations towards this practice, such as threats to research integrity and concerns about a lack of transparency of companies' practices. Furthermore, participants mentioned issues of scholarly access to corporate data that might both disadvantage the academic research community and create issues of scientific validity. Academic-company partnerships could be a positive development for the advancement of scholarly behavioral research. However, strategies should be implemented to appropriately guide collaborations and appropriate use of corporate data, like implementing updated protocols and tools to govern conflicts of interest and the institution of transparent regulatory bodies to ensure adequate oversight of academic-corporate research collaborations.
PMID: 36662904
ISSN: 1932-6203
CID: 5426432

In Reply

Bayefsky, Michelle J; Caplan, Arthur L; Hoskins, Iffath A
PMID: 36441934
ISSN: 1873-233x
CID: 5373882