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Reader performance in the ultrasonographic evaluation of oropharyngeal carcinoma

Faraji, Farhoud; Padilla, Ericka S; Blitz, Dana; Wenderoth, Meghan B; Blanco, Ray G; Kawamoto, Satomi; Sheth, Sheila; Hamper, Ulrike M; Fakhry, Carole
OBJECTIVE:To examine reader performance in evaluating oropharyngeal anatomy on ultrasonography. MATERIALS AND METHODS/METHODS:Ultrasound images of the oropharynx comprising normal and malignant anatomic variants were organized into slideshows. Slideshows were administered to 6 readers blinded to participant tumor status and with varying experience reading oropharyngeal sonograms. A training slideshow oriented readers to images of the oropharynx with and without malignant lesions. Readers then evaluated images in a test slideshow for tumor presence and marked orthogonal long and short dimensions of the tumor. Results were analyzed for accuracy, sensitivity, specificity, inter-reader agreement, and measurement error relative to prospectively-identified reference measurements. RESULTS:Eighty-seven percent of base of tongue (BOT) sonograms were identified correctly by a majority of readers. In identifying BOT tumors, median accuracy, sensitivity, specificity, and Fleiss's kappa were 79%, 73%, 85%, and 0.51, respectively. Median measurement error in the long and short axes for BOT tumors was -2.6% (range: -40% to 29%) and -2.6% (range: -56% to 156%), respectively. Eighty-four percent of palatine tonsil sonograms were identified correctly by a majority of readers. In identifying tonsil tumors, median accuracy, sensitivity, specificity, and Fleiss's kappa were 77%, 74%, 78%, and 0.41, respectively. Median measurement error in the long and short axes for tonsil tumors was 3.8% (range: -45% to 32%) and -6.5% (range: -83% to 42%), respectively. CONCLUSIONS:Overall, US has clinically useful sensitivity for identification of oropharyngeal carcinoma among readers of diverse clinical backgrounds and experience. US may be useful for the evaluation of features such as tumor dimensions.
PMID: 29362115
ISSN: 1879-0593
CID: 2970272

From Academia to Government to Industry: A Strange Journey and Its Lessons

Zerhouni, Elias; Fishman, Elliot K; Horton, Karen M; Sheth, Sheila
PMID: 29055609
ISSN: 1558-349x
CID: 2912822

How Technology Is Changing News and Our Culture: Lessons From Elections 2016 and Davos 2017: Tech, Media, and the Newsroom of the Future

Tanner, Christy; Fishman, Elliot K; Horton, Karen M; Sheth, Sheila
PMID: 28838748
ISSN: 1558-349x
CID: 2695132

The Importance of Brand Name

Freeman, Marissa; Fishman, Elliot K; Horton, Karen M; Sheth, Sheila
PMID: 28624303
ISSN: 1558-349x
CID: 2695142

The Cost of Unconscious Bias and Pattern Recognition

Abramson, Jenny; Fishman, Elliot K; Horton, Karen M; Sheth, Sheila
PMID: 28284674
ISSN: 1558-349x
CID: 2695152

Renal Papillary and Calyceal Lesions at CT Urography: Genitourinary Imaging

Kawamoto, Satomi; Duggan, Peter; Sheth, Sheila; Miyamoto, Hiroshi; Kazi, Zubair N; Fishman, Elliot K
PMID: 28076022
ISSN: 1527-1323
CID: 2695162

ACR Appropriateness Criteria((R)) on renal failure

Remer, Erick M; Papanicolaou, Nicholas; Casalino, David D; Bishoff, Jay T; Blaufox, M Donald; Coursey, Courtney A; Dighe, Manjiri; Eberhardt, Steven C; Goldfarb, Stanley; Harvin, Howard J; Heilbrun, Marta E; Leyendecker, John R; Nikolaidis, Paul; Oto, Aytekin; Preminger, Glenn M; Raman, Steven S; Sheth, Sheila; Vikram, Raghunandan; Weinfeld, Robert M
Imaging plays a role in the management of patients with acute kidney injury or chronic kidney disease. However, clinical circumstances strongly impact the appropriateness of imaging use. In patients with newly detected renal dysfunction, ultrasonography can assess for reversible causes, assess renal size and echogenicity, and thus, establish the chronicity of disease. Urinary obstruction can be detected, but imaging is most useful in high-risk groups or in patients in whom there is a strong clinical suspicion for obstruction. Computed tomography, computed tomography or magnetic resonance arteriography, and percutaneous ultrasound-guided renal biopsy are valuable in other clinical situations. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.
PMID: 24865874
ISSN: 1555-7162
CID: 2695172

ACR appropriateness criteria post-treatment follow-up of renal cell carcinoma [Guideline]

Casalino, David D; Remer, Erick M; Bishoff, Jay T; Coursey, Courtney A; Dighe, Manjiri; Harvin, Howard J; Heilbrun, Marta E; Majd, Massoud; Nikolaidis, Paul; Preminger, Glenn M; Raman, Steven S; Sheth, Sheila; Vikram, Raghunandan; Weinfeld, Robert M
Although localized renal cell carcinoma can be effectively treated by surgery or ablative therapies, local or distant metastatic recurrence after treatment is not uncommon. Because recurrent disease can be effectively treated, patient surveillance after treatment of renal cell carcinoma is very important. Surveillance protocols are generally based on the primary tumor's size, stage, and nuclear grade at the time of resection, as well as patterns of tumor recurrence, including where and when metastases occur. Various imaging modalities may be used in the evaluation of these patients. Literature on the indications and usefulness of these radiologic studies is reviewed. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.
PMID: 24793039
ISSN: 1558-349x
CID: 2695182

Transcervical ultrasonography is feasible to visualize and evaluate base of tongue cancers

Blanco, Ray Gervacio F; Califano, Joseph; Messing, Barbara; Richmon, Jeremy; Liu, Jia; Quon, Harry; Neuner, Geoffrey; Saunders, John; Ha, Patrick K; Sheth, Sheila; Gillison, Maura; Fakhry, Carole
BACKGROUND: Base of tongue (BOT) is a difficult subsite to examine clinically and radiographically. Yet, anatomic delineation of the primary tumor site, its extension to adjacent sites or across midline, and endophytic vs. exophytic extent are important characteristics for staging and treatment planning. We hypothesized that ultrasound could be used to visualize and describe BOT tumors. METHODS: Transcervical ultrasound was performed using a standardized protocol in cases and controls. Cases had suspected or confirmed BOT malignancy. Controls were healthy individuals without known malignancy. RESULTS: 100% of BOT tumors were visualized. On ultrasound BOT tumors were hypoechoic (90.9%) with irregular margins (95.5%). Ultrasound could be used to characterize adjacent site involvement, midline extent, and endophytic extent, and visualize the lingual artery. No tumors were suspected for controls. CONCLUSIONS: Ultrasonography can be used to transcervically visualize BOT tumors and provides clinically relevant characteristics that may not otherwise be appreciable.
PMCID:3907536
PMID: 24498138
ISSN: 1932-6203
CID: 2695192

CT of gallbladder cancer and its mimics: a pattern-based approach

Deshmukh, Swati D; Johnson, Pamela T; Sheth, Sheila; Hruban, Ralph; Fishman, Elliot K
On computed tomography (CT), gallbladder pathology may be detected incidentally or as the etiology of symptoms that prompted imaging. Accurate pathologic diagnosis can be challenging, however, due to overlapping appearances of malignant and benign gallbladder disease. This pictorial essay takes a pattern-based approach to CT of the gallbladder, to help the radiologist formulate the proper differential diagnosis.
PMID: 22581235
ISSN: 1432-0509
CID: 2695212